Blood Testosterone Threshold for Androgen Deficiency Symptoms
jcem.endojournals.org/cgi/content/full/89/8/3813
"… A key finding of this study is that the threshold for androgen deficiency symptoms occurs at highly reproducible blood testosterone concentrations in hypogonadal men.
That is, men reach a distinctively individual trigger level for androgen deficiency symptoms and seek retreatment at similar blood testosterone concentrations each time. Yet, this trigger level differs widely between men. This replicability reinforces the notion of a measurable threshold at which androgen deficiency symptoms occur but recognizes that this threshold differs between individuals.
Although this threshold varies from very low to values above the lower limit of the eugonadal reference range, on average it approximates the lower limit of the eugonadal reference range for young men.
[Size=4]The determinants of this symptomatic threshold are unknown but presumably include genetic polymorphisms that influence androgen sensitivity[/size] (25), although the magnitude of this genetic determination is uncertain (26). "