Novel drug regenerates erectile nerves damaged by prostate surgery

I found this article interesting and didn’t see it posted here.


Albert Einstein College of Medicine


Researchers have developed a topical drug that regenerates and restores the function of erectile nerves damaged by radical prostatectomy, the most common treatment for localized prostate cancer. The drug was tested in rats.


Whoa, nerve regeneration, that is awesome! Very cool

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Very interesting. I briefly looked over the article, will read it in full depth when I have time.

It’s funny though because just the other day when I was trying to interpret why the 2nd most overexpressed cluster of genes was "“metabolism of RNA” in the Baylor study meant.

And while I was searching I got actually got to read a little bit about these RNAi (RNA interference). Apparently they are able to suppress over 60% of our protein coding genes.

  • Friedman et al. estimate that >45,000 miRNA target sites within human mRNA 3′UTRs are conserved above background levels, and >60% of human protein-coding genes have been under selective pressure to maintain pairing to miRNAs. Direct experiments show that a single miRNA can reduce the stability of hundreds of unique mRNAs."

Unstable RNA leads to increased RNA metabolism, so that was the link I found to Baylor. They do not discuss that cluster at all in the paper so I have no clue if it’s related.

But I find it reasonable. Also worth nothing HDAC inhibitors only regulate about 2% of our genome. Quite the difference in potential impact.

Edit: Source.


When will this be available? Pretty amazing stuff from the sound of it.

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I’m not sure I posted this the day the hospital (Montefiore in the Bronx) tweeted about it, but I forwarded it to the foundation and asked they contact them. I was told they did, but haven’t heard any more. Perhaps if those researchers were contacted by more people, it may speed up the testing from rats to humans.


If they contact you let us know. If they are looking for human trials I’d sign up.


Praying for this


Same sounds ground breaking


@NewYorker have you heard anything more on this?

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No, nothing more. Maybe the foundation can keep in informed to these various initiatives? Regardless, I’ll reach out the researchers. The worst they could do is not respond.

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Please do and thank you

Anything with this since?

Or nothing because they’re still gettin it through?