Nolvadex question

Therapeutic Efforts Pharmaceutical
#1

Dr. Crisler put me on Nolvadex for a month, but I had a question to any of you that are familiar with it. I told myself I wouldn’t take any med after finasteride without doing a ton of research first. I see that Nolvadex can have sexual side effects as well.

I assume the benefits outweigh the sides in this case, but I thought I would ask anyone who tried the nolvadex if they had success and/or if the ended up with any of the sexual sides from it.

Thanks a lot for any advice or feedback on this drug.

#2

Are you taking the Nolva to treat libido/ED issues? I can say (for at least myself) that Tamoxifen actually did cause me some libido/ED issues. However, everyone on the steroid forums have posted otherwise how it helps them fight gyne and other high estrogen problems. I’ve tried it 3 different times for a week or so long and everytime it’s pretty much killed my libido or caused me to have very weak erections. It always went away about 2 weeks after I stopped taking it. I tried it 3x to make sure it wasn’t something else or in my head that caused it. I’ve read several places where it causes loss of libido and even ED.

If you do take it just be cautious of it’s effect. If you feel improvement than great! I was taking 10mg in the AM and 10mg in pm.

Do you have labs that suggest to take Nolva? High Estradiol or Total Estrogens? Why did Crisler put you Nolva?

#3

If Nolvadex can possibly make things worse, would taking something like DIM do the same? I know DIM doesn’t block E but helps metabolize it, does this make a difference? And what would be the reason for lower E causing loss of libido/ED?

#4

Some ppl swear by DIM saying it helps metabolize the good Es and rid the bad. Not sure if there are clinical studies to show DIM lowers Estradiol similar to Arimidex. DIM is pretty much capsuled broccoli.

Like everything else in your system, hormones are present for a purpose. Everyone (some more for one sex over another) has Estradiol (most potent type of Estrogen). Taking Arimidex or anything else and lowering Estradiol too much causes a hormonal IMbalance. It’s such a fine line when doing any type of HRT…unless you have numbers that are well out of the range it’s best to avoid any type of HRT…it’s a balancing act once you do start HRT. Like TRT…you end up needing HCG to keep testes working and Arimidex to keep Estradiol low. If Estradiol goes too low than you have issues similar to when it’s too high…only w/out blood tests you’ll never know cuz u can’t draw blood every week and so u’ll have to guess why ur having issues…and from there u change you dosing in the dark…hoping to find a balance.

Jack

#5

I have only taken it for a day and a half so far. How long did you take it before you noticed the ED and libido decrease?

Thanks a lot.

#6

I noticed it after 3 or 4 days. There wasn’t anything else that I noticed other than difficulty to get an erection, no morning/night wood at all, and erections were very weak when I did get one.
How much are you taking?

#7

I’m supposed to take 40mg per day for one week, then 30 for a week, then 20 then 10 then get completely off it after that, but I really don’t want to deal with ED considering that’s what I’m being treated for.

#8

What does your blood work reveal that suggests taking Nolva? Did you meet with Crisler personally or is this via phone consultation.

It’s easy to just try Nolva as it supposedly works for so many ppl to fight gyne and restart their HPTA…but one should have some labs that call for it. My labs have normal/ideal Estradiol levels but my Total Estrogens were very slightly above the max range so I tried it. I didn’t experienc anything but negative effects. THAT’S JUST ME THOUGH.

Jack

#9

I met with him personally and then had blood and urine work ups. My T levels were great in the morning but dropped off drastically throughout the day and my estrogens were a bit high but not too much. He believed the estrogen blocker would allow my t levels to build and then level out.

#10

How was your LH ? low or normal

#11

My apologies…I’m still fairly new to the terminology. What is LH?

#12

Luteinizing Hormone.

A hormone signal sent from your Pituitary that tells your testes to produce Testosterone.

If its low and Testosterone low = possible Secondary Hypogonadism.

If it’s high and Testosterone low = possible Primary Hypogonadism (testicular failure).

Do some research on Google and read the stuff in the “Other Studies” section of this website for more insight.

#13

Nolvadex (brand name for Tamoxifen) like all SERM medications and aromatase inhibitors has the ability to increase erections and libido or kill both of them stone dead.

It all depends upon the initial level of estradiol, the dosage involved and ultimately how it affects the amount of estradiol able to work in your endocrine system.

If there is too much estradiol able to work in your system you have Ed and libido issues, too little and yuou have the same problem.

So it is about having the right amount of estradiol in your body in order to function correctly.

It is key that pathology highlights a need for such medcations prior to use. If you have ED and a low libido that might be down to a whole host of causes, low testosterone or thyroid hormone fro instance, it is not neccessarily down to elevated E2. If you just assume you have a high level of E2 and throw Nalvadex at it then you can end up with too little estradiol able to work in the body and make matters worse.

P.S

It is difficult to dose Nolvadex and SERM medications because estradiol blood test are rendered useless given the fact that they do not lower estradiol in the blood but block its action and the estrogen receptor sites. If aromatase inhibitors are used, then estradiol is lowered in the blood and an estradiol blood test can be used to correctly alter dosing. That said Nolvadex is useful in other regards and can be the right tool in the hands of a competant endocrinologist.

#14

Does this mean that if youve tried Clomid and had no improvement, then it likely that your problem is not in fact and E problem? Generally speaking.

Also why do guys get the emotional sides when on Clomid, if it actually blocks E effects? That seems backwards.

#15

No.

e.g You could easily have not lowered the effects of estradiol enough or you could be on too high a dose and lowering estradiol too much and missing the window of health- going from too high to too low.

You cannot generalize, you need to have the correct pathology and be able to correctly interpret such in light of symptoms and case history.

Too high or too low can cause these problems, the same is true with libido and erections. I could detail further but what is the point given you know the bottom line.