There is a whole field of medicine based on this simple molecule I didnt even know existed, or I should say multiple disease states or afflictions that this substance could treat.
HA plays a pivotal role in the homeostasis of respiratory apparatus.
In the upper airway HA is primarily involved in the regulation of vasomotor tone and gland secretion and it significantly contributes to nasal mucosal host defense, stimulating ciliary clearance.
On Tissue Repair.
Hyaluronic acid (HA), the main component of extracellular matrix, is considered one of the key players in the tissue regeneration process. It has been proven to modulate via specific HA receptors, inflammation, cellular migration, and angiogenesis, which are the main phases of wound healing.
https://www.researchgate.net › publication › 298420271_…
(https://www.researchgate.net/publication/298420271_Hyaluronic_Acid_in_Inflammation_and_Tissue_Regeneration)
Hyaluronic acid (HA), the main component of extracellular matrix, is considered one of the key players in the tissue regeneration process.
Hyaluronic acid is a major component of skin, where it is involved in repairing tissue
Collagen / Hyaluronic Acid Matrices
for Connective Tissue Repair
Interestingly, we identified the receptor for hyaluronic acid, as significantly associated with androgen stimulation.
More proposed connections here.
Skin Aging manifests primarily with wrinkles, dyspigmentations, texture changes, and loss of elasticity. During the skin aging process, there is a loss of moisture and elasticity in skin resulting in loss of firmness finally leading to skin sagging. The key molecule involved in skin moisture is hyaluronic acid (HA), which has a significant water-binding capacity.
These results show that ROL increases skin expression of HA, a significant contributing factor responsible for wrinkle formation and skin moisture, which decrease during aging. Taken together with the activity to increase collagen, elastin, and cell proliferation, these studies establish that retinol provides multi-functional activity for photodamaged skin.
Keywords: Aging; HAS3; Hyaluronic acid; Hydration; Moisture; Retinol.
The analysis of 3H-glycosaminoglycans showed that in the epidermis retinoic acid elevated the amount of labeled hyaluronate by 70%,