New Member from Italy, still using Minoxidil (is that bad?)

Welcome to our community. Please fill in the following template as a way of introducing yourself, and helping others to understand your background and situation.

Where are you from (country)? Italy

How did you find this forum (Google search – if so, what search terms? Via link from a forum or website – if so, what page? Other?) Searching on Google about PFS

What is your current age, height, weight? 33, 185cm (6.1 if i’m correct), 75kg (165 lbs)

What specific drug did you use (finasteride, dutasteride, saw palmetto, isotretinoin/Accutane, fluoxetine, sertraline, citalopram, leuprorelin, etc…)? Finasteride, Topical 5% minoxidil with anti androgens.

What dose did you take (eg. 1 mg/day, 1 mg every other day etc.)? 1 mg/day first four years, 1mg day alternating the days (one yes and one no) for other 3.5 years, 1/mg day three days a week in the last year

What condition was being treated with the drug? Male Pattern Baldness

For how long did you take the drug (weeks/months/years)? Around 8.5 years

Date when you started the drug? July 2014

Date when you quit the drug? March 2023

Age when you quit? 32

How did you quit (cold turkey or taper off)? Cold Turkey (i hope this is correct because the last year of taking it i was using 1mg a day, three days a week, so not everyday like i used to do)

How long into your usage did you notice the onset of side effects? It’s difficult for me to have a date about that, around 2019 and i had side effects on the sexual side but i was using an anti depressant, zoloft, back then.

What side effects did you experience that have yet to resolve since discontinuation?

Check the boxes that apply. You can save your post first, then interactively check/uncheck the boxes by clicking on them. If your symptoms change, please update your list.

Sexual
[ X] Loss of Libido / Sex Drive
[ X] Erectile Dysfunction
[ ] Complete Impotence
[X ] Loss of Morning Erections
[X ] Loss of Spontaneous Erections
[ ] Loss of Nocturnal Erections
[X ] Watery Ejaculate
[ X] Reduced Ejaculate
[ ] Inability or Difficulty to Ejaculate / Orgasm
[ ] Reduced Sperm Count / Motility

Mental
[ X] Emotional Blunting / Emotionally Flat
[ ] Difficulty Focusing / Concentrating
[ ] Confusion
[ ] Memory Loss / Forgetfulness
[ ] Stumbling over Words / Losing Train of Thought
[ ] Slurring of Speech
[X ] Lack of Motivation / Feeling Passive / Complacency
[ ] Extreme Anxiety / Panic Attacks
[ X] Severe Depression / Melancholy
[ ] Suicidal Thoughts

Physical
[ ] Penile Tissue Changes (narrowing, shrinkage, wrinkled)
[ ] Penis curvature / rotation on axis
[X ] Testicular Pain
[X ] Testicular Shrinkage / Loss of Fullness
[ ] Genital numbness / sensitivity decrease
[ ] Weight Gain
[ ] Gynecomastia (male breasts)
[ ] Muscle Wastage
[ ] Muscle Weakness
[ ] Joint Pain
[X ] Dry / Dark Circles under eyes

Misc
[ ] Prostate pain
[ ] Persistent Fatigue / Exhaustion
[ X] Stomach Pains / Digestion Problems
[X ] Constipation / “Poo Pellets”
[X ] Vision - Acuity Decrease / Blurriness
[ ] Tinnitus (ringing or high pitched sound in ears)
[ ] Hearing loss
[ ] Increased hair loss
[ ] Frequent urination
[ ] Lowered body temperature

[X ] Other (please explain) Dry Eyes, Dry Skin.

What (if any) treatments have you undertaken to recover from your side effects since discontinuation of the drug? Tried probiotics and an anti-inflammatory medicine for my bowel, but they just worked a little bit during the treatment.

If you have pre or post-drug blood tests, what hormonal changes have you encountered since discontinuing the drug (please post your test results in the “Blood Tests” section and link to them in your post)? I’ve done blood work two weeks after quitting the drug, and they were seen by an andrologist, he said they were ok, never done other bloodwork since then (it was 11 months ago)

Anything not listed in the above questions you’d like to share about your experience?

Tell us your story, in your own words, about your usage and side effects experienced while on/off the drug.

Hi everybody, first of all i’m italian, so english is not my native language, sorry for the mistakes.

Started using Finasteride 1mg a day (generic one, not propecia) around July 2014 with 2% topical Minoxidil, than in September 2016 (always 1mg finasteride a day) switched to 5% topical minoxidil with anti androgens in the lotion, here is the lotion:

Progesterone 1%
Ciproterone Acetato 1%
Minoxidil 5%
Triamcinolone acetonide mg 5
Idrocortisone butirrato 0,07 %
17 Alfa Estradiolo 0,025%
Transcutol
Acqua Depurata (’‘Depured water’’)
Alcool q.b. a 100ml

Then in 2017 switched to 1mg/day on alternating the days (one yes and one not) and in november 2022 switched to 1mg/day three days a week.
Always used the lotion everyday from September 2016 to November 2022 (i should have used 3ml/day but i was a complete idiot and used more, i guess around 5/6ml sometimes because with mid-long hair i thought i couldn’t irrorate the scalp effectively) and then switched to 5 days a week in November 2022.
I used it until mid Februray of this year (2024) then switched to just 5%Minoxidil with no anti-androgens added.

First problems (low libido/ED) i’ve seen were around December 2019, but back then i was using an anti depressant (Zoloft) so i blamed it.
Then i’ve got on and off Zoloft a couple of times and libido was really low, it improved a little bit when i was off.

Around November 2021 i started having bad gut issues, i was always constipated, my poop was hard as little rocks, with a lot of mucus and some blood sometimes, i had even stomach cramps and started having problems digesting milk/cheese and stuff like that (never had that problem before) but i didn’t know it was a side effect until these last months i discovered this forum.

Around 20 march 2023 i was with a girl and i was able to get an erection with oral stimulation but not able to keep it for a penetration, and besides that i had still a low libido so i wasn’t excited about the whole thing.
My skin was really dry, my eyes too were dry, they were ‘‘burning’’ at the end of the day and they were slightly red, sensitive to light too.
I stopped that day but kept using the lotion with anti androgens.
I had bad depression episodes, going to the therapist since 2016, getting slowly better day by day even if sometimes my mind ‘‘crashes’’

Now it’s been around 11 months, eyes are less dry even if it’s not completely resolved, i guess around 70% back to normal (unfortunately i’m talking just about eyes), skin is way more soft, less water retention on my body, gut is always messed up but slightly better, i have now almost no cramps and the poop is kinda softer (sometimes but not always). but i still dont have normal stools. (there is always mucus and some blood)
I’ve gained some nocturnal erections (with Finasteride they were gone) even if they weren’t rock hard, but no morning wood, i can get an erection if manually stimulated but it’s not that much good to have sex if i wanted to (i’m single now) and i can lose it easily.
Semen is less watery, more thick/dense and whiter, even some volume more, but i think it isn’t back to pre-fin state.
Libido was slightly better but nothing close to normal, last weeks it went down…

My mental state was not that good (it goes up and down, the more i think about PFS the more it goes down), then i started having two days of walking in nature a week when i can at the beginning of December 2023, and it helped for my mind, i was feeling better (even if ‘‘feeling better’’ is a big word for people with our problem).
But last weeks were bad because i was thinking that this state could be persisent so my mood was bad and i almost had no erections.

Two weeks ago i stopped with the topical Minoxidil lotion with anti androgens (do you think they were bad for my healing???) and just started using only topical Minoxidil 5% 2.5 ml/day five days a week, with no other added stuff, do you think i should quit that too?

Maybe in these weeks i should do bloodwork again (last time i tested TSH, 17 beta estradiol, LH, FSH, Prolactine, Testosterone and Free Testosterone and they were in the ranges) but i hadn’t checked DHT

And see a doctor to talk about my gut health, last time they didn’t help me.

Sorry for my bad english. Hope that all of us could be fine one day.

I’ ve read somewhere that us users we should do a poll on this site, but i can’t find it, if i can be useful doing that no problem…

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Three months have passed since i quit the anti androgens too on the minoxidil lotion (and 14 months since i quit finasteride)

Skin is less dry, same thing for the eyes, i guess skin is almost completely recovered and the eyes are almost at it (while i was on fin they were really dry and burning severely).

Got a little bit more hairy in the wrist zone, beard, legs, pubic zone and chest, even if i’ve never been an hairy guy even before finasteride.
Hairs (in the scalp) are obviously a little bit thinner but not that much.

Libido was getting a little bit better around half of april (not enough to have sex by the way) and then it crashed really low almost three weeks later, don’t know why. Now it’s really low, something like around april '23 when i quit finasteride. Strange thing, i was asking myself if it could be that one of the anti androgens that i used in the lotion was progesterone, and maybe stopping that worsened the thing? 'Cause i’ve red that some guys used progesterone as a treatment for PFS.

Got an abdomen echograpy scan (is that correct or the english term is ‘‘ultrasound’’?) and it says that the prostate and bladder are ok with regular dimension.

Gut issues are still there even if they’ve changed a little bit, now it’s more diahrrea then ‘‘rock hard’’ feces.
Got blood test and stool test done and they’ve said that i’ve got Helycobacter Pylori and that i’m gluten sensible (not celiac). Strange because no one in my family has got is like that.
They told me to go gluten free for three months and then try to eat gluten for about a month or two and see how it’s going.
For the Helycobacter they’ve prescribed me medications (Pylera for 10 days and Esomeprazole for 5 weeks)
With depression symptoms is going better even if there are some days where i feel depressed but overall it’s going better, some days i even feel clear (as long as a guy in his 30s with ED can say that).
Some days i even feel ‘‘physical rage’’, like wanting to break something physically, never had that kind of feeling during finasteride use, and i’ve never been a rage guy in my life, quite the opposite to be honest.

Sperm is more thick/dense and more white, when i was feeling some libido more it was even more in quantity terms, but not now.

Spider veins on legs are still there (cold feets in the winter and hot feets during this period).

I have to focus more on exercising (cardio and weight lifting) cause i didn’t do that much in this period.

Don’t know what to think, everything is getting a little bit better except sexual sides that are worse and i don’t understand why…

Started to scale minoxidil (now four times a week) because I want to stop it too, I’ve read too many posts of people with side effects from it, hope to stop completely by the end of the next month.

The next week I’m starting the helicobacter pylori treatment.

Kinda silly that I’ve written that mentally I was getting better because these days I had severe anxiety, never happened like that since December of the last year.
But I’m not ok with the idea of taking medicines for that (anxiety) , I’m scared that they might lead to another crash.

Testicles seems a little bit fuller in size these days, especially the right one (the left one is smaller because of varicocele, I had the intervention pre finasteride usage)

Libido still very low…

After minoxidil stop I was thinking about doing blood tests. Last time it was on April 2023 (the andrologist told me they were ok) , and then to see and endocrinologist ( not far away from home there is an endocrinologist that is in contact with Professor Melcangi)

Right now I don’t have a girlfriend but I was thinking to have a prescription for Cialis and to see if libido and ED would improve.
That worked for you?
Basically I think my problem is more lack of libido, I don’t get excited…

I want to change the topic title but I don’t know how to do that… Just “New member from Italy” cause probably minoxidil usage for us is bad too😂