Nacle blood tests

Member Stories Lab Tests
#1

I’m 24 years old. View my story here: propeciahelp.com/forum/viewt … fe46118d2d

I have been to an andrologist. He made get an eco-doppler ecography aswell as a hormone profile. The ecography shows a second level varicocele in the left testical and will be needing operating after i get a sperm test done.

FSH: 1.71 ug/dl 1.7-12

LH: 1.64 mUI/ml 1.1-7.0

E2: 65.9 pg/ml < 62

PRL: 9.95 ng/ml 2.1-18

Testosterone: 6.19 ng/ml 3.00-10.60

SHBG: 25.3nmol/l 13-71

DHT: 658 pg/ml 300-1200

DHEA-S 3.78 mcg/ml 1.3-3.8

The doctor doesn’t seem to be concerned of my estradiol level.I don’t agree with him on that.He said that if I was feeling low libido he could prescribe me testosterone gel,I declined firmly.I dont’ think it’s the better solution.

Evidentally my estradiol level is off target and this to him isn’t a problem.What am I supposed to think?What do you guys say?
Is it a good thing to get progesterone checked too?Anything else?

I would like to know what Hypo thinks,I know he is quite educated on this matter… Any other comments or views are welcome.

#2

Your estradiol is very high, outside of range.

Sounds like your gyno issues are from high E2… I would try either Brocolli Treatment (in Naturals section of forum) or try DIM supplements to start. If no changes in a few months then try Arimidex at a very low dose to bring it down.

Progesterone would be good to check as well on your next blood tests.

#3

Thank you Mew for the advice and sorting my post out…Before trying anything i’ll try to recontrol E2 levels, no doctor over here is likely to prescribe an AI or SERM and probably wouldn’t even cycle TRT, I’ll try enlighting the question though. If have no success and my estradiol levels are still high,I’ll try diindolylmethane and maybe someother natural remedy to start with…I’ve heard milk thistle and curcumina do a good job,so as vit b6. Anyone have any experience with these?

#4

Last week I got a GNRH stimulation test here in Italy…Not quite sure how to interpretate the results though.I got them done around 10.30 in the morning

GNRH 100ug administration

TIME: 0’ 15’ 30’ 45’ 60 ’ 90’
in minutes

LH: 1,7 9,9 16,6 17,8 17,9 16,0
1,0-9,0 mUI/ml

FSH: 2,1 2,7 3,4 3,7 4,0 4,1
2-15 mUI/ml

T: 7,0 no no no no 6,5
3,50-8,60 ng/dl

E2: 94,7 no no no no 50,8
<75 pg/ml

These are the results for now, I still have to go back to the andrologist with them.
Both LH and FSH raised progressively so that could cut out both types of Hypogonadism,I guess.Not at all sure why both Testosterone and Estradiol decreased after 90 minutes.
Testosterone seems to be in normal range,but Estradiol is still too high and I’ve got the feeling that when I visit my DR again it’s still not gonna be an issue with him(FUCK!!!).Anyhow I got some 22.5mg zinc tabs on the hand with copper,I’ll try popping 2 of them a day on my on bases…
Got some DIM supplement on the way too,maybe I’ll that if the zinc only doesn’t help.
The DIM supplement is the following:http://store.yahoo.com/marcella75/dim60caps200mg.html
It’s the only one I can purchase here in Italy directly from the UK…Do you think it’s a reliable source?The active compound dosage seems ok,but doesn’t seem to have any special delivery system.

#5

All the blood tests look fairly good with the exception of estradiol.

Often when estradiol is high emotional problems occur. I would not be suprising if you felt uncharacteristically tearful from timte to time or at least emotionally a little less stable. It could also cause either or both low libido and erectile dysfunction.

If a blood test is overtly high and even outside of the normal range then it cannot be said to be normal, to do so is to make a mockery of the definition. By being outside of the normal range it must be abnormal.

I think that you would almost certainly benefit from a prescribed course of an aromatase inhibitor such as arimidex. I think if dosed sensibly it would lower your estradiol and alleviate your symptoms.

I think a free testosterone test would be useful prior to prescription, just to see if your estradiol is causing problems relating to your androgen status.

Of note:

Overtly high estradiol often causes the development of gynecomastia, male breast development is categorically not something that you should risk suffering/have to suffer because of a urologists lack of understanding of the issues involved. If the treating doctor continues with this flawed and poorly educated position then you will need to seek a second more worthwhile opinion and treatment elsewhere.

I think you should take the hypogonadal checklist and see what score you get- I think it can be found on the second or third page of the general forum. I would hope that you do not score too high symptomatically, but it would be interesting to view.

Please feel free to comment on anything I have mentioned in this or any other post that you feel is of relevance.

P.S

Your dynamic GnRH test showed that when primed your hypothalamus/pituitary work, it shows a correct male response and an intact hypothalmic pituitary link/axis.

Just being ultra careful here…I take it that your testosterone level was tested independently of the GnRH test? I mean I take it that your testosterone level was taken separately, either on a differing day or prior to the GnRH test?

This is very important because a testosterone test after a GnRH test is completely invalid as an assesment of endogenous testosterone production.

#6

Hypo my first testosterone level was taken contemparily to the gnrh injection so of no interaction.the second level was taken 90 minutes later after the injection(around midday),same reguarding to the E2 level. Lh and fsh were tooken every 15 min from 10.30 to 12.
I have my hypogonadal score on my profile.thanks for the immediate response

#7

I would think you would need an estradiol test that was independent of the GnRH test. In fact I think it was quite silly to have tested estradiol off of the back of that test given the fact that it could easily give a false reading.

I looked at your profile but I didn’t see the score you mention, maybe I missed something?

If your estradiol level is overtly high on a second test then I stand by my comments. If however it is much lower then that would change matters.

I think an estradiol and free testosterone test would help clear matters up in terms of the sex steroids.

If no problem can be found in this regard, but libido is still low then I would consider checking free T3, free T4 thyroid hormones and 24 hour urinary cortisol.

#8

Ok that is very clear. I’ll get those two parameters controlled alone as soon as possible.

this is the score from my profile:

#9

It will be interesting to see how your results come back.

#10

Hypo I was checking on the second last draw I’ve had and there was Free Testosterone measuring

Free T 27 pg/ml

E2: 65,9 pg/ml

SBHG 25,3

Total T 6,19 ng/ml

DHT 658 pg/ml

Do you think the Free T level here is attendable?

#11

What are the reference ranges for each of the above tests?

I ask because different labs calibrate their tests and equipement around differing values and so it is never enought to simply know a result without also having the applicable ranges.

#12

TOTAL TESTOSTERONE: 6.19 ng/ml 3.00-10.60

ESTRADIOL: 65.9 pg/ml <62

FREE TESTOSTERONE: 27 pg/ml 10-45

SHBG: 25.3 nmol/l 13-71

DHT: 658 pg/ml 300-1200

#13

Based on the reference range you have supplied for the free testosterone I would say that it is less of an issue than the elevated estradiol would appear to be, but that it could still be a little too low for you to function well.

You need to have the estradiol checked again independently of the GnRH test.

If it is still high then you might well benefit from a well prescribed course of arimidex to lower the estradiol. This would have a knock on effect of increasing your free testostreone- more importantly it would lower the estradiol which could be causing problems independent of testosterone.

For what it is worth that is my take on matters.

#14

These are my estradiol a free testosterone ranges checked.

Free T: 23 pg/ml 10-45

E2 : 44,42 pg/ml <62

Estradiol is slightly lower but I had been supplementing with zinc 80 mg for 4 days till the day before the bloodtest…I feel slightly better as it comes, the zinc is surely doing something.I know that this might be sudden but I am definately feeling more energy all around. I have less muscle stiffness when I excersize and my voice is slightly deeper pitched.
But i think my estradiol should come down lower so I’m hoping my doctor can prescribe me Arimidex, maybe 0,5 mg once every 2-3 days.

#15

You would probably feel much better if your estradiol was between about 22-30 pg/ml. On which note a precribed course of arimidex correctly dosed and monitored might help you feel a lot better. The fact that you feel slightly better with the zinc is not on the least suprising given the fact that it is a natural but very weak aromatase inhibitor. Zinc though will not do what is required, so you need to get your doctor to give you a trial prescription on said medication.

#16

If only it were that simple Hypo :cry: …the andrologist I saw today said that he still think they are fine no matter what i told him…I’m gonna try visiting an endo for the third time,if I still have no success I’ll try imploring my gp for prescription and carefully dose myself.i would prefer to collaborate with a qualified and upfront doctor though. :unamused:

#17

What country do you live in?

Also what is the nearest city?

Just asking to see if there is anything I can come up with- a long shot but with a go.

#18

Parma in Italy

#19

I have found three endocrinologists that list reproductive endocrinology as an area of interest in Italy. They are not in Parma, but they might (might being the operative word) be able to help you. I have no idea as to have forward thinking endocrinologists are in Italy or any idea if these people are any good, but it is worth giving them a call- you have nothing to lose. The endocrinologists were listed on the AACE (American Association of Clinical Endocrinologists) website so their credentials at least should be good.

Piernicola Garofalo, MD
Via CA Dalla Chiesa 10
Palermo, 90139
ITALY
Phone: 39-3483823375
Interest Areas:
Disease of Pregnancy
Pediatric Endocrinology
Reproductive Endocrinology
Thyroid Dysfunction
Osteoporosis

Camillo Giammartino, MD
Azienda Ospedalierqa S. Maria
Largo Tristano da Joannuccio
Terni, 05100
ITALY
Phone: 744205387
Interest Areas:
Adrenal Disorders
Cancer
Pituitary Disorders
Reproductive Endocrinology
Thyroid Dysfunction

Patricia Lentini, MD
Via Vincenzo Tomassini
Rome,
ITALY
Phone: 06 35510609
Interest Areas:
General Endocrinology and Metabolism
Obesity
Reproductive Endocrinology
Thyroid Dysfunction
PCOS

If this doesn’t help then then I apologise- it is the best I could come up with given your location.

#20

Thank you Hypo, these are quite far out as it comes from where I live,anyhow I’ll see what I can do. I’ll keep the thread dated as soon as I get any new news