My Theory: Body type that has low tolerance for drugs. Anyone else believe this?

General Discussion
#1

I am 22 and have always had a low tolerance to medications. Prior to taking Propecia, I would always take the smaller or half dose of X medication and get the same results as if i had taken a full dose. I am also prone to get the side effects associated with the drug. A 1/2 dose of Nyquil makes me feel like a zombie the next day. I was prescribed adderal and would only need 1/4 of the dose to get the effects yet I still couldnt sleep 10 hours after i had taken the the pill. Etc, Etc.

Not surprisingly, propecia gave me great hair growth after only a week of usage but i also got all the side effects.

Not only medication, but I noticed that my muscles would grow after just one visit to the gym and if I took a few days off I could notice them getting smaller.

Has anyone else felt that they had a low tolerance to medications or noticed similar changes in body type as a result of physical activity or lack of? Does anyone know why my body is so vulnerable to medications/physical activity and if this may be a reason why I am experiencing side effects from Propecia?

#2

I noticed exactly the same for my body …i just needed small dose of meds to get better when i was sick… i think that my body has always been very sensible to everything …even smoking weed with friends i just needed smaaller dose to get high compared to my friends and alcool too…so i believe it could be possible . 1mg finasteride was too high for my body and it didn t tollerate it…looking at our sides i think noone has tollerated it for sure…said this what could help?

#3

i can’t tolerate viagra, it cause to me a big pain in my eyes (it’s one of the side effects)

#4

Can anyone say that they do NOT have a low tolerance for drugs and drug side effects? I would be really interested to hear if those who are suffering from propecia side effects never noticed that they were vulnerable to side effects from other medications. Our livers are responsible for digesting drugs so maybe these side effects are related to poor liver function?

I also only need a small amount of weed to get high. Not sure that this would be related to taking medications. As far as alcohol, I can drink as much as anyone else but always got real bad hangovers. And alcohol is also digested by the liver.

Any other thoughts?

#5

yes , its quite likely you and many people have a fast phase 1 and slow phase 2 detoxification pathway.all it means is the liver changes a toxin into a form that phase 2 can eliminate but that intermediate toxin is much more powerful than the original.in alcohols case the intermediate toxin is 10 times more toxic than the alcohol itself.

the large load of toxins gets dumped into the phase 2 section which cannot handle it so you get these toxic symptoms.i did the liver detoxification profile test about 8 months ago , i posted the findings on here.
propeciahelp.com/forum/viewt … ght=#10242
do some research on the terms if you are interested.

#6

hi RUFF. so what about your liver now?are you better and to help it you just had a better diet and coenzyme q10 or something else?

thank you

#7

I never had a low tolerance for drugs and I still got fucked up from this poison.

#8

me too… i never had problems with drugs

#9

im sensitive to most supplements/pills so i use barleygrass powder + maca powder , good diet , some exercise and 30 mins of infra red sauna per day.
i’m marginally better than i was 8 months ago , i dont get itchy skin when im hot/exercise anymore.also my libido has improved since then.

#10

infra red sauna is very good for detoxification. I used one a few times before I decided to fast and always felt more rested after each use.

#11

yeh its good , i have one of those portable fold up ones.the surround is made in china but the heat ‘pads’ ie the part that does the heating are made in japan.i’d say i sweat about 400-500ml in a 30 min session , more if i let the unit warm up beforehand.

im thinking about doing another liver test in a month or so , see if those numbers have improved.

#12

Calcium D Glucarate assists with phase 2 liver detoxification. Very small doses of Grapefruit juice (10ml 3 times a day or so) is said to slow down phase 1 liver detoxification so phase 2 can have a chance to keep up.

#13

Hi J89

I think it’s been a while since you’ve posted. How are you doing these days?

Are you still on TRT?

Hope things have been better for you. Thanks.

#14

I’m very sensitive to all drugs or meds too. Tall, lean, and mean :wink:

#15

hey guys , try supplementing with magnesium , apparently it is used in over 300 detoxification processes in the body.i use a few grains of epsom salts (magnesium sulfate) in a glass of water twice a day.dont buy supplements with mag oxide , you wont absorb them well.

#16

How am I doing? Absolutely crap.

#17

I do feel better after taking epsom salts, but only in a very small quantity. I tried taking a little too much this morning and…holy diarrhea batman! LOL
Good thing it’s a Sunday and I don’t need to go anywhere :slight_smile:

#18

All medications I took so far and currently take are well tolerated by me.
the only thing that fucked me up is finasterid.

for any other medications I have hardly any noticeable side effect so far.

#19

I have become extremely sensitive to all drugs. So much that I cannot take ibuprofin. I was always sensitive but now it’s off the charts…

#20

I am tall, lanky and extremely sensitive to medications. I have extremely high metabolism and can pretty much eat anything without gaining weight.

I had side effects to migraine headache medication when I was young. I had to take oxycontin after surgery and it made me feel like crap. I had horrible viagra side effects. Also I get really bad hangovers, sometimes after only one or two beers.

This makes me think my finasteride side effects might be related as well.