I decided to make this thread just to track a protocol I am starting with the aim to increase androgen receptor density. According the current AR theories, this actually seems like the opposite of what you would think we need to do. However, I have seen enough recoveries / improvements by people taking compounds that raise AR density that its encouraged me to test myself.
My current state is that my energy/fatigue/brain fog symptoms are 80-95% depending on the day. I’ve spent years focusing on adrenals and thyroid and Cortef is always god sent to me for these symptoms.
Sexually, is where I am still at 0-10%. PDE5is only sporadically work these days and my urologist is willing to do a penile implant which I may do once insurance covers.
PROTOCOL (cycles of M-F for 2 weeks, then off 2 weeks, repeat)
-ALCAR 2g 3x a day
-Capsaicin 1x day (MST Capsimax)
-Mucuna Pruriens Extract 1x day
-Intermittent Fasting (shooting for 11-13 hour daily fasts, basically skipping bfast)
All of these above have been shown in studies to increase AR density.
I have seen articles that state Forskoline and Niacinamide also do, but when I looked at the research it seemed to indicate that they “activated” AR (like androgens do) but necessarily increase density with a vague mention of increasing “sensitivity”
I was always a bit of an ectomorph / hardgainer, which tells me maybe my AR density has always been low. I read a study that stated that people who respond to weight lifting the best don’t have higher androgen levels, but instead have higher AR density.
Tribulus (mainly protodoiscin) also increases AR density. But if you don’t get the right one it may make you worse for various reasons. If I do enough cycles of my protocol without benefit then I may start cycling Tribulus.
What is interested is that in 15 years of PFS, the only thing that ever improved / recovered my sexual symptoms was a product that had mucuna pruriens and tribulus in it… both increase AR density. However, I wasn’t cycling it and it eventually wore off.
Other vitamins/herbs that are a part of my staple that I will continue…
-Pregnenolone (a few times a week)
-Phenibut (1x ever week or two)
-Rhodoila (a few x a week)
-Cordyceps a few x a week)
-Vit D (a few x a week)
-K2 (w Vit D)
-T3 (25mcg per day split in 2 doses)
-Cortef (only as needed… 5-10mg maybe 1x a week or every 2 weeks)
I should also state that I have tried ALCAR in the past, its actually been something I’ve taken at low doses on and off for a while, it helps mentally but never anything close to recover. I suppose I am hoping that combining it with other AR density increasers as well as doing a good job of avoiding random 5ari’s that are in foods + the cycles will be what helps…