I wouldn’t say you’re coping. It is more so just coming to accept the horrific changes and finding a new normal as @Dknighten said in an interview once. It’s something I can’t do and don’t ever see myself doing. Sure the loss of proper sexual function and physical pain is torturous but for me the worst of it all is the anhedonia and depression. I’ve seen people have anhedonia for decades and I just wonder what is the point of suffering like that for so long? Anyways, maybe someday will escape this disease or atleast future people will not have to endure this hell.
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my only comfort is that someday this nightmare will end
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3/19/2026 Update
Finishing up two weeks of DHT-E and E2 this week. Nothing crazy. Will add in 500 MG Sodium Valproate XR nightly tonight and eventually titrate up the VLP and DHT-E. E2 will stay the same. The other day I crashed into GABA-A dysfunction hell from light exercise (akathisia, flight/fight anxiety, sleep disturbances, and just feeling even worse). I’ve had a few windows of musical anhedonia lifting, spontaneous erections, random physical improvements, and the fatigue improved (mostly replaced by awful GABA-A dysfunction). I have dreams but wake up in a terror like Ryan Russo did with Post Lions Mane Syndrome which is basically nuclear PFS for some. May use BPC-157 and TBU-500 subQ for the venous leak. Hopefully I recovery. Fck this 1/4th life.
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Wasn’t he using PEA to offset some of those symptoms during his protocol? Might be worth a shot.
Yeah, in the second half after he got rid of the anhedonia and most of the other symptoms
3/24/2026 Update
Running DHT-E, E2, and Sodium Valproate XR for four months straight and will periodically up the doses of DHT-E and VLP. If I don’t get the switch at four months so when I come off, it’s game over PFS. If I do, that’s great I’ll run PCT and hopefully be fully recovered. Not hanging around with PFS sorry guys.
@tiredofthispostfin
Have you done DHT / Estradiol labs? How do they look?
How’s Sodium Valproate so far?
@michael.holzgraefe Hey man, funny I was just going to make an update. I have not. VPA is an angelical compound that nukes anxiety. I no longer have fatigue, sleep is better, libido windows, ED improving, nighttime horniness, musical anhedonia windows, and honestly, I feel better about getting out of this hell. I can look at a woman on the streets and feel something sometimes. I’ll be running this for another five months straight. I’ll be doing labs soon probably in a week or so.
Side note - I’ve always liked the design of this forum. Much better than PSSD forum or Reddit.
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@tiredofthispostfin
Sounds great! Very happy for you!
I hope the good progress continues! Keep us posted!
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Do research about islamic fasting and how its done the correct way not just food and water deprivation. Do it for a week and try to wake up early so that you fast for a good 9 or 10 hours. Like i said its not just food and water deprivation so read how its done correctly. After a week i assure you that you will become a muslim after the improvements you are going to see. Do it and give the feedback
Yeah, I’m not too sure about that
Im not asking you to try sodium valporate, or tribulin or the crazy stuff ive seen in this forum, im asking you to try something for a week seeing how bad your situation is you have nothing to lose.
i have tried fasting, it did nothing for me
Also tried a waterfast for 10 days, did nothing; if anything I’ve lost a bit of muscle. 
AFAIK the people who reported benefits eventually came back and said the benefits faded.
Again, i am talking about islamic fasting and not the intermittent or water fasting. There is absolutly no way you did the correct way for the islamic fasting and you did it by waking up early and not just waking up 4 or 5 hours prior to the sun goes down. Again islamic fasting the correct way, by waking up early for 10 days.
6/3/2026 Update
6/1/2025 was the last day I ever took finasteride. I remember it like it was yesterday. Little did it know what I was experiencing would not dissipate on its own and in fact get worse with time. The gift that keeps on giving.
Anyways, I have alright fluctuating libido, the fatigue/anhedonia is unbearable some days, still low to no anxiety, and the ED is complete (expected). Will have to continue running its course and then see afterwards.
So tired of this disease. Doctor Will Powers seems interesting. Hopefully he’s onto something as I’d enjoy not having PFS forever.
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