Permanent changes in human gene expression from just one pill or like the recent guy said (which I’m not all sure what to believe) 1/4 of a pill is a little hard to buy into.
For me, these rapid changes in gene expression could possibly be explained, the keyword being possibly, by rapid microbial shifts.
Unlike the human genome, the microbial genome is rapidly modified through diet and drugs.
Microbes in turn could affect human gene expression.
October 26, 2016 / Genomic Medicine
How Trillions of Bacteria in Your Body Can Change Your Genes
https://health.clevelandclinic.org/billions-bacteria-bodies-change-genes/
I’ll also throw in this really simple concept.
Microbial endocrinology: the interplay between the microbiota and the endocrine system
The new field of microbiome research studies the microbes within multicellular hosts and the many effects of these microbes on the host’s health and well-being. We now know that microbes influence metabolism, immunity and even behavior. Essential questions, which are just starting to be answered, are what are the mechanisms by which these bacteria affect specific host characteristics. One important but understudied mechanism appears to involve hormones. Although the precise pathways of microbiota-hormonal signaling have not yet been deciphered, specific changes in hormone levels correlate with the presence of the gut microbiota. The microbiota produces and secretes hormones, responds to host hormones and regulates expression levels of host hormones.
Thanks for your efforts btw.