Mefipriston - a potential solution for those suffering altered levels of progesteron

Therapeutic Efforts Pharmaceutical
#1

For all of those who have a proven, tested elevated progesteron that supress your natural 5 alpha reductase output there is a light in the tunel.

If you suffer a long term altered levels of progesteron, that might be a first ever true solution. Altered levels of progesteron turn you to be more less like a pregnent woman.

We have to follow what is going on with this drug being sold as “abortion pill”.

There are some trials going on with this drug. These trials are established for a different purpose then stopping pregnency.

Hopefully it will be manufacured for a different desease and we will be able to recover with this.

If you can provide any info about the potential investication on this drug, I would be glad to hear that.

#2

Mefipriston and Org 34517 are being tested as Future Treatments for Depression, Anxiety, Sleep Disorders, Psychosis, and ADHD… <--------- nothing new to us.

Their action goes by blocking the GR chanel responsible for the transport of glucocorticoids mainly progesteron.They are supposed to have a positive impact on HPTA system.

Mefipriston and Org 34517 stimulates HTPA by blocking antagonistic action to GK (glucocorticoids- not sure if I translated correct).

There is also a study going on with Org 34517. We have a phase II going on, so hopefully it is not so far from the market release.

Look at the link bellow:

neurotransmitter.net/newdrugs.html

If finasteride and Dutasteride exagerated the action within these GR channels we might have something like a perfect product for us.

I also wonder what is the action of GHB that have helped to recover a guy called Paul Waters.

Maybe GHB also stimulates HPTA by antagonist action to GR receptors!! We should look for this.

I think this is something good for Mew to search for, so that he will be able to find a proven backround to these prommising (also for him) speculations.

What do you think Mew?

PS: Guys from my team! Remember, we have a low LH, FSH and imbalance in progesteron. Propably decreasing of the GR channel will help us to regain HPTA action.