Matis tests

I just posted my story in the Members Story section – propeciahelp.com/forum/viewtopic.php?p=3764

These tests were made for three different labs. Beside i put the ranges that were on the tests. The first was the only one that i made while was on fina.
Any advice is very very welcome.

25/05/04

Total T: 303,30 ng/dl ( 241,0 - 827,0)
TSH: 4,00 uUI/mL (0,4 - 7,0)
T3: 119,70 ng/dl ( 75,00 - 220,00)
T4: 6,30 ug/dl (5,4 - 13,7)

19/10/06

Total T: 4,2 ng/ml (3,0 - 10,0)
TSH: 1,36 mcUI/ml (0,3 - 6,0)
T4: 6,9 mcg/dl ( 4,8 - 12,5)

26/10/06

Total T: 4,6 ng/ml (3,0 - 10,0)
Free T: 16,5 pg/ml (18,0 - 36,0)
Prolactina: 14,5 ng/ml ( - till 15 ng/ml)
LH: 6,0 mUI/ml (1 - 12)
FSH: 3,3 mUI/ml (1,4 - 18)

19/01/07

Total T: 337 ng/dl (132 - 813)
SHBG: 14nmol/L (13 - 71)
FSH: 3,0 mU/ml (2,0 - 17,5)
LH: 5,0 mU/ml (1,4 - 7,7)

18/04/07

Total T: 253 ng/dL (132 - 813)
Free T: 21,6 pg/mL (8,8 - 36,0)

14/06/07

Total T: 293 ng/dL (132 - 813)
Free T: 18,1 pg/mL (8,8 - 36,0)
TSH: 1,09 uUI/mL (0,3 - 4,5)

30/07/07

TSH: 2,40 uUI/mL (0,3 - 4,5)
S-dehidroepiandrosterona: 222 ug/dL (125 - 620)

Your testosterone is too low, if it remains that way then you have hypogondism that requires treatment.

Thank you for the reply Hypo.

Do you believe that the action of fin for those who suffer permanent sides is to drop testosterone level? That would be the cause of the symptoms?

I think that it makes a lot of sense, but it’s very difficult one doc agree with this opinion. Besides the fact that most of them don’t admit the possibility of finasteride cause permanent sides (at least those that i met), the hormonal replacement for young man is still a taboo and for them if the level of T is in the range, it’s all fine.

That’s the reason why i tried TRT by myself for two months without sucess. How much time of TRT is necessary for to feel improvement in the symptons?

Finasteride does cause hypogonadism in some men that much is a fact to those in the know. Whether or not this is the only cause of problems and side effects or not is open to debate.

The fact is your testosterone is very low for a young man and it is generally too low period.

The US reference range for ng/dl in the measurement of male testosterone usually has a bottom figure of around 300 ng/dl.

There is no way on earth that this reference range goes as low as what you have been quoted. That is complete rubbish and should not be trusted.

If I had a endocrinologist using that reference range and not questioning I would fire their ass immediately.

On which note;

If you tell me what city you live in I will provide you with contact details for endocrinologists in your area who will hopefully know the difference between their ass and their elbow- something your current endo does not.

Like i said, the possibility of hypogonadism makes a lot of sense to me, i think that too many of my symptoms can be of hypogonadism like less libido, depression, memory problems.

I will make some visits to docs to take their opinions and make a full hormonal test (Hypo i send you a private message). If i have to do hormonal replacement no problem, if this gonna make i feel better is great. I have nothing to lose, only to gain.

After i receive my test i will post here and explain the route of my treatment.

Had a bit of a problem with the site tonight so I am best posting what you need in here.

You will need to phone a few of these endos up and vet them yourself. I do not know these endocrinologists so choosing the one that seems the most likley to help you is a judgement call for you…hope one of them can help.

Silvio Roberto Correa, MD, FACE
Av Rio Branco 4332
Umuarama, PR, 87501-130
BRAZIL
Phone: 55-44-3622-6393
Interest Areas:
Adrenal Disorders
Diabetes Mellitus
General Endocrinology and Metabolism
Growth Disorders/Growth Hormone
Reproductive Endocrinology
Thyroid Dysfunction
Other

Paulo Osny May, Jr, MD
Avenida Beira Mar Norte 2060
Florianopolis, SC, 88015-400
BRAZIL
Phone: 011 4832241111
Interest Areas:
Geriatrics
Growth Disorders/Growth Hormone
Lipid Disorders
Reproductive Endocrinology
Thyroid Dysfunction
Menopause

Givan Cortês Nascimento, MD
Avenida Colares Moreira, Número 555
Renascença II
São Luís, Maranhão, 6507-0550
BRAZIL
Phone: (98) 3236-5527
Interest Areas:
Adrenal Disorders
General Endocrinology and Metabolism
Pituitary Disorders
Reproductive Endocrinology
Menopause

Hermes Pardini, MD
Rua Aimores, 33 - 3 andar
Bairro Funcionarios
Belo Horizonte, MG, 30140070
BRAZIL
Phone: 005531-3228-6571
Interest Areas:
Adrenal Disorders
Diabetes Mellitus
Ectopic Endocrine Syndromes
General Endocrinology and Metabolism
Growth Disorders/Growth Hormone
Lipid Disorders
Metabolic Bone Disorders
Nuclear Medicine
Parathyroid Disorders
Pituitary Disorders
Reproductive Endocrinology
Thyroid Dysfunction
Osteoporosis

Adriano Oliveira Seixas, MD
Rua Dom Constantino Barradas, 120 Apto124
Sao Paulo, Sp, 04134-110
BRAZIL
Phone: 11 5068-2633
Interest Areas:
Adrenal Disorders
Cancer
Diabetes Mellitus
Disease of Pregnancy
Ectopic Endocrine Syndromes
General Endocrinology and Metabolism
Geriatrics
Growth Disorders/Growth Hormone
Hypertension
Lipid Disorders
Metabolic Bone Disorders
Neurosurgery
Obesity
Nuclear Medicine
Nutrition
Parathyroid Disorders
Pediatric Endocrinology
Pituitary Disorders
Reproductive Endocrinology
Endocrine Surgery
Thyroid Dysfunction
Other
Osteoporosis
PCOS
Menopause

Ieda T. N. Verreschi, MD
Rua Botucatu
740 P.O. Box 20266
Sao Paulo, SP, 04023-900
BRAZIL
Phone: 55-11-55791232
Interest Areas:
Growth Disorders/Growth Hormone
Reproductive Endocrinology
Other

Lucio Vilar, MD
Rua Minas Gerais, 64/01
Ilha do Leite
Recife, Pernambuco, 50270-400
BRAZIL
Interest Areas:
Diabetes Mellitus
General Endocrinology and Metabolism
Pituitary Disorders
Reproductive Endocrinology
Thyroid Dysfunction

Thank you man :smiley:

I got today the results of my test. It was made at 10 a.m. Excuse me for my english, i will try be as clearly as possible.

Here they are:

Albumin: 4,70 g/dL (3,5 - 5,0)
T3: 100 ng/dL (80 - 210)
T4: 6,3 ug/dL (4,5 - 11,5)
TSH: 1,27 uUi/mL (0,3 - 4,5)
FSH: 3,0 mU/mL (2,0 - 17,5)
LH: 4,6 mU/mL (1,4 - 7,7)
Prolactin: 8,1 ng/mL (2,0 - 14,5)
Total Testosterone: 461 ng/dL ( 241 - 827)
SHBG: 18 nmol/L (13 - 71)
Cortisol: 12,0 ug/dL (5,5 - 20,0)
DHEA-S: 322 ug/dL (125 - 620)
Estradiol: 32 pg/mL (10 - 40)

It’s a big surprise to me this T level. The last three tests i have done it was between 253 and 337. This raise could be a good sign, but i have not noticed any improvement in my mental sides or libido. The only thing i noticed was a improvement in the frequency of morning erections.

The estradiol seems a little high for me. Maybe that is the problem. I saw in the internet some articles connecting increase of estradiol with a increase of allergic reaction by the mast cells. Since i began the use of finasteride i developed very strong symptoms of allergic rhinitis (if all the other sides weren’t enough), that i did not have before. This rhinitis last until today and keeps strong.

sciencedirect.com/science?_o … 837b14bd2d

jeb.biologists.org/cgi/content/full/207/3/437

"Mast cells occur in all classes of vertebrates (Galli, 1990) and are the only cells that possess high-affinity receptors for IgE and synthesize histamine (Galli, 1990; Scharenberg and Kinet, 1995). It has been demonstrated that estrogen treatment is effective in inducing mast cell proliferation in different vertebrate tissues (Gibbons and Chang, 1972; Gaytan et al., 1986; Mohanty and Chainy, 1992). Although the mechanism controlling changes in mast cell number (MCN) is still unclear, it is generally accepted that estradiol acts on mast cells (Modat et al., 1982; Krishna and Terranova, 1985). Indeed, estrogens have been shown to affect mast cell secretion (Shelesnyak, 1959; Conrad and Feigen, 1974; Krishna and Terranova, 1985; Slater and Kaliner, 1987); estradiol increases histamine and serotonin secretion and this effect is counteracted by tamoxifen (Vliagoftis et al., 1992). "

If the estradiol level is the problem, so i think that a treatment with tamoxifen/clomid could give a good response, despite the T level do not demonstrate hypogonadism.

I would appreciate very much advices of you guys.

watch your thyroid first, it has begun elevating in 2007 , order full thyroid panel, check your oral tempratures, your first step is fixing your thyroid,
depression and mood swings, swollen eyes will be ok after you stabilized your thyroid

dont pop every drug, wait and check your blood test, wait for a stabilized blood test that remains same, after that find if you have thyroid problem, solve that.

adrenal fatigue will b the next treatment.

have you tested reverse t3, free t3, free t4 and thyroid antibodies?
these are required.

hi matis. can you pls reach me?