Yap.what you are describing has a term: “andropause”.
Also men age and lose levels of androgens. It doesn’t happen that abruptly as in women, but the andropause happens over time - in every men.
Symptoms are very similar to PFS:
Loss of stamina, erectile dysfunction, loss of libido, loss of vitality, loss of muscle mass, increased risk for depression, thin dry skin…
That’s why I call PFS oftentimes accelerated aging of men.
Prof. Z. from University Muenster is using The “Aging Males’ Symptoms (AMS)” questionnaire on PFS patients to assess their symptoms.
Also interesting, the general degree methylation of DNA increases with aging. Something we observed at least on a single gene in PFS: SRD5A2.