Low dose testosterone without HCG

Therapeutic Efforts Pharmaceutical
#121

I am trying to work out why I can never get my glucose under 5. Apparently cortisol decreases the effectiveness of insulin. So if your cortisol is high you will be more insulin insensitive. The weird thing is that my blood cortisol is high. But siliva was low. Im still waiting for my transcortin results.

Insulin
Cortisol counteracts insulin, contributes to hyperglycemia-causing hepatic gluconeogenesis[10] and inhibits the peripheral utilization of glucose (insulin resistance) [10] by decreasing the translocation of glucose transporters (especially GLUT4) to the cell membrane.[11][12] However, cortisol increases glycogen synthesis (glycogenesis) in the liver.[13] The permissive effect of cortisol on insulin action in liver glycogenesis is observed in hepatocyte culture in the laboratory, although the mechanism for this is unknown.

Gastric and renal secretion
Cortisol stimulates gastric-acid secretion.[18] Cortisolā€™s only direct effect on the hydrogen ion excretion of the kidneys is to stimulate the excretion of ammonium ions by deactivating the renal glutaminase enzyme.[19] Net chloride secretion in the intestines is inversely decreased by cortisol in vitro (methylprednisolone).[20]

My cells should be very insulin sensitive as I exercise 2 times a day. It is know that low cortisol can cause digestion issues.

So one thing indicates high cortisol another thing indicates low cortisol.

#122

Abstract
INTRODUCTION:
The hypothalamic-pituitary-adrenal axis is known to be related to abdominal symptoms, and the relationship between abdominal pain and cortisol secretory patterns has been previously investigated using a cross-sectional approach. Here, we investigated the effect of day-to-day variations in salivary cortisol and dehydroepiandrosterone-sulfate levels on abdominal symptoms in healthy individuals.
METHODS:
Eleven college students (4 males and 7 females) participated in this study. The participants were asked to collect their saliva immediately after awakening and before bedtime for eight consecutive days. They also completed a questionnaire about abdominal symptoms before bedtime. The linear mixed model was applied to analyze the effects of the day-by-day variability or the 8-day average adrenal hormone level (at awakening, before bedtime, slope from awakening to bedtime) on abdominal symptoms.
RESULTS:
The day-to-day variability of cortisol levels before bedtime was negatively related with loose stool, while the day-to-day variability of the cortisol slope was positively correlated with loose stool. A low 8-day average dehydroepiandrosterone-sulfate level at awakening was positively related with frequent bowel movements, loose stool, and long bouts of severe abdominal pain. Likewise, a low 8-day average dehydroepiandrosterone-sulfate slope was positively related with long bouts of abdominal pain.
CONCLUSIONS:
Low cortisol levels before bedtime and a steeper diurnal cortisol slope during the day may be related to bouts of diarrhea during the day.

#123

just tested blood glucose again 5.9 :neutral_face: I have not eaten since last post. I am starting 2 feel a little more hungry too.

#124

Have not been hungry again. I applied about 25 mg of transdermal preg to see what happens. Trying to work out why I had appetite for the first 10 days I was on testosterone.

#125

At something a while ago blood glucose was 8.2.

#126

Before sleep I applied about 30 mg progesterone cream now I am lying her and canā€™t sleep also took 1 gram gaba 30 mins ago but feel wide awake. I guess it is the cortisol boost from both t and program and maybe the pregnant I took today.

#127

Managed to fall asleep last night. Woke up digestion not great. Did not seeem to sleep that well. It is strange that such a low dose of testosterone is having so much of a stimulating effect on me.

#128

I woke up about 10:30.

Did some exercises about 11:30. Took 15mg preg when waking up. Tested blood sugar its 12:40. 4.7. Lowest reading so far.

Do not what the cause of it is.

#129

I put on preg, did an 8 KM walk came back tested blood after 30 mins, 5.89, then in another hour 5.0, then in another 50 mins 5.8. Dont feel hungry. Starting to feel tired/sleepy. Tomorrow is my testosterone shot

Feeling a bit negative that we will not fix this stuff even if hormones are at the right levels.

#130

I have been having pesimistic(maybe realistic) thoughts about all of this to day. I suspect its the pregnenolone.

Its been 4 years for me. I have tried a lot as you can see from my blood tests. Right now the testosterone has helped my energy a lot, stopped my cystic acne that was causing ugly scaring on my butt. In the first week I felt really good without libido but that did not last.

The increased energy makes me want to stay on this testosterone as before my energy would crash very easily. And I was getting more scars all over my but. Acne came back on but at 45mg e3d test but less than that seems to clear it.

Now I am in Sydney, the only reason I am here is to try and fix this. I have been living in Thailand and was loving it, but then this happened.

I am trying to formulate a plan of action for the next 6 months.

Trying to increase DHT, perhaps my DHT has gone low from the shots. I will apply testosterone cream to my scrotum.
Try adding proviron to my low dose of T when I get back. I want to ensure I have high levels of androgens and normal levels of estrogens.
I also have some DHT prohormone which I have not tried yet.
I will then try some aromasin as this is what robocopp swears by and is taking evey day. I did recover libido on arimidex but was unable to reproduce this.
I may try injectin masteron to see what happens.
I may try trenbolone if I can get it to increase androgens without increasing estrogens in my body.
May try DECA to increase the level of anabolic hormones in my body. My teeth are sensitive since stopping fin and now my gums are receeding. I have always maintaind very good dental health but now its all falling apart thanks to finasteride.
When I took gaba the first few times I got very hard wood. Perhaps that was from an increase in growth hormone.
I may try more growth hormone peptites or secretalogs.
I feel like I am living because I am trying to recover, if I can not recover I do not know if I really want to live as I will not be able to do any of the things I have planned to do in my life. My tollerance to stress is now really low, probably because of the free cortisol issue.

#131

Getting quite a lot of twitches. Probably from the PREG synthesizing into estrogen.

#132

Last night seemed to fall asleep pretty easily. That is probably because it was 3rd day after shot.

I injected 27.5mg test, and i also applied about 500MG test to scrotum in an attempt to increase DHT which may or may not be low on shots. I am trying to work out why during the first 10 days I felt very good and even after day 2 appetite came back.

Now appetite is no good.

I exercised an hour or so ago. Intense for 10 - 15 minutes. Blood sugar an hour later is 5.3 temp 36.8.

#133

Ok I ate many hours ago. Blood glucose is now 6.4. I should be almost onto my 3rd meal of the day. I have only eaten one and not hungry at all. I am going to have a strong coffee and see what that does.

Don;t understand how injecting testosterone can lead to a low appetite? I mean it was low before but I could eat now I feel full.

#134

5:12 - Here, had a coffee about 1 hour. Have not drunk any in 4 weeks. And before that never really had a full strength coffee.

As I said, I have much more energy on the testosterone. And it seems the coffee has made little difference to how I feel. Maybe it has made it a little harder to concentrate. But before I took the test I would to drink coffee to get some energy. Now it makes no difference. This indicates my cortisol has been boosted with the coffee. This could explain the pain I was getting in my back when starting the testosterone. Maybe my adrenals were expanding to pump out the cortisol. I do not have that pain any longer.

I have not eaten for about 6 hours, blood glucose 5.4 - not hungry.

#135

Now yawning and feel sleepy

#136

8:04 have not eating for like 7 hours and had only one meal since I woke up today at about 9:30 blood sugar is 5.2. I could eat but im not really hungry stomach does not have that empty feeling.

#137

Only ate 3 small meals today 2 would have been more than enough. The transdermal testosterone on the testicles only deemed to have possible bad effects like negative thinking twitches and today my appetite was so bad.

#138

do you feel any water retetion like on your chest and around ankles? watch closely.

#139

nope nothing like that. I am pretty sure for me high estrogen = twitches but maybe its another hormone that is causing the twitches like DHEA itself. Because I get it with DHEA and Preg along with negative thoughts.

Im starting to think my loss of appetite could be high cortisol. That would explain why I can not sleep. Cortisol blunts the effect of insulin.

But not sure why I was hungry in the first week. Maybe the cortisol was ramping up. But the thing is my testosterone is not super high or anything.

Again last night was unable to fall asleep this is because yesterday morning I did my injection. I had to take gaba to fall asleep.
The night before the injection was able to fall asleep.

The question is, why is testosterone making it hard for me to fall asleep? If my levels were not to high, I should be able to sleep fine. So does this indicate my levels are too high? On my blood tests total t was in top 1/5th of range, free T middle of the range. That was 3 days after the injection. But because I am having such a small dose it seems wierd.

My testicles are also as hard as ever. And I am pretty sure they got harder after I quit fin.

#140

No offence, but maybe you could space out your posts about this instead of posting every mundane detail. It bumps your thread to the top of the section all the time and is unnecessary - you could simply give a bigger digest of what is happening every couple of weeks for example. The forum isnā€™t a platform for your diary.