I was wondering if anyone else has gone to get tested for autoimmune disease? One thing that is interesting is that people with multiple sclerosis have low allopregnenolone. I went to a rheumatologist and allergist a year ago and they found nothing (but they did very basic tests). However, I was speaking to a doctor recently and he said finasteride may have triggered some sort of autoimmune response. Autoimmune disease has been documented from statin and accutane use. Could it be auto-antibodies against some enzyme or cells that is preventing our bodies recovering? I am in the process now of getting re-examined by doctors for autoimmunity. From what I understand, the scientists havenāt really tested for autoimmune disease.
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I have sent this question to pfsfoundation.org that how the possibility of autimmune anti bodies have been ruled out, if it has.
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Iām not saying it has to be autoimmune, but what really worries me is that it seems as though not enough time was spent analyzing whether it could be autoimmune. Autoimmune diseases are sometimes hard to diagnose due to the fact that you donāt know what your body has antibodies against. That, and the fact that multiple sclerosis patients also have low allopregnenolone makes me feel that the scientists should seriously look into it.
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I am pretty sure they are looking into all sorts of different aspects of this, and non scientific minds like us questioning it does not really serve any purpose, to be completely honest.
Some threads along this line
Lennon, you know nothing about if āaspects of thisā are being looked into - why make this stupid comment?
Maybe its time to stop giving out your ignorant, misleading āadviceā to other people?
Thanks!
Source on the MS/allo link?
I know whatās being looked into (donāt ask me or PM me). Nothing Lennon said was incorrect. Why do you gratuitously use quotation marks? Nearly half your posts are in the (shit) theories section, all of which have been of zero value. While we were working on getting the foundation started, not only were you wasting time on talking about things you know nothing about, you were childishly mocking those taking action, then whining how you canāt āfall in love with a woman.ā Hopefully moderation becomes more strict as we continue to progress.
Donāt think itās autoimmune. I feel like I turned a corner at the 10 month mark, others have as well.
Lennon, you know nothing about if āaspects of thisā are being looked into - why make this stupid comment?
Maybe its time to stop giving out your ignorant, misleading āadviceā to other people?
Thanks!
ā¦
[b]Haha, Oscar, you are truly a fool, and so very in the dark. You are truly a worthless member, and constantly mislead people.
It is ok though, it really makes no difference what you think, or theorize for that matter.
You should truly stop wasting peoples time on this forum (even though we both know you wont).
You are perhaps the most tragic member on this board, and it has nothing to do with your symptoms, but with your character. For some reason, I get this feeling you were always a foolish, miserable sod, even before ever touching finasteride.
Do not ever refer to me in your posts again. I have absolutely no respect for you as a person, and I consider you an obstacle when it comes to group unity and progress towards a treatment.
AND STOP MISLEADING PEOPLE WITH YOUR BULL SHIT DR. GOOGLE![/b]
PS
By āaspects of THISā I meant āaspects of our conditionā ā¦ personally Oscar, I think people like you who are a total distraction should be banned from this forum so that the people who are rational can continue to focus on the foundation and towards a possible treatment, but as we all know, it is pretty loose around here, and stupidity such as yours almost seems welcome, sadly.
I should not let you irritate me so much I suppose, but to be honest, you have been annoying for so long, it is a bit difficult. I just want you to know Oscar, that if I ever come face to face with you, perhaps when we give skin biopsies for research, or even if it is to celebrate a cure ā¦ I am going to pound your mother fucking face in.
These words mean nothing to you now I am sure, but mark my words, if I ever do come face to face with you, I will teach you manners and respect, which obviously your parents never did ā¦ you are miserable, useless man who should have been banned form this forum already because you are nothing more than a negative influence and a total distraction from progress.
I truly hope you will be banned. We do not need you. At least, no rationale thinking person needs you.
ncbi.nlm.nih.gov/pubmed/21908875
Many have not. At 3 years off i can say my wheels have stopped spinning in the mud because the engine conked out.
If it was autoimmune, how could that be treated??/
So, after speaking with my doctor, there are 7 tests which will be positive in all autoimmune illnesses (usually the criteria is if 2 or more of these are positive then the patient is likely to have an autoimmune illness) these include: ANA, RF, C3, ESR, CRP, WBC, ferritin. I was test for these a year ago and they all came back negative. Iām going to try these tests once more just for my own reassurance.
This not true, i am negative on all of those, except C3 which i have not been tested for and have crohns disease.
Many auto immune disorders have no cure.
I am confused. We have previous studies of what finasteride does to neurosteroids in rat studies, basically ācompletely abolishingā the effects of neurosteroids. Now we have that the sample tested by Melancogi exhibiting diminished levels of neurosteroids in the
CNS. Furthermore our physical manifestations and symptoms are reflective of such. So why do we think itās some autoimmune disease?
What is the reason why our 5a reduced metabolites resemble that of someone who is still on finasteride?
This is the crux of the problem, what is stopping our 5a reduced steroids from returning to normal.
degreen when you were tested for these tests, were you on any multi vitamins or Vitamin D3? I am asking this because my CRP was very high, Ferritin low and WBC very high.I was scanned to find the reason but dr could not find the reason. He said high wbc means there is infection but where, we donāt know., Dr had called me to tell that I was at risk of heart attack. I was very sick those days, was taken to ER twice. Anyway I started high dose of vitamin D3 and my all tests became negative. My point is multivitamin or Vitamin D3 only, can alter the results falsely. When any body goes for these tests he should stop every thing few weeks before the tests.
Are 2 or more of these present in MS? Are 2 or more of these present in other autoimmune diseases of enzymes? (Addisons, Hashimotos etc). Good luck anyway.
I donāt remember. When I repeat them I will stop all supplements at least two weeks prior, so Iām not going to get the blood test any time soon. Apparently though none of the readings were even borderline, they were all well below normal so nothing to indicate autoimmune. Thing is though is that our symptoms of inflammation may be caused by lack of allopregnanolone since it is anti-inflammatory itself. Muscle twitches, brain fog, and possibly sexual sides could all be because of low allopregnanolone.
I will say this however, if you are concerned that it may be autoimmune, look up Dr. Terry Wahls, watch her videos on youtube and strictly implement her diet for at least 6 months. She was able to put her MS into remission (apparently cured). That is probably the only chance to cure is if it is autoimmune. Chemotherapy and bone marrow stem cell transplant procedures will cause sexual dysfunction themselves so forget that.