Its your theory, so prove it right or wrong or youre wasting everyones time
haha ordering right now buddy its open in the other tab right now - by the way im hoping for the love of GOD that this ISNT what we have this would be aweful. a disease that makes your AR not work and the more testosterone you give it the worse it gets
thank you for doing that wontgiveup
no worries! whats another hundred bucks at this point
mda.org/publications/Quest/e … /sbma.html
Mice with an SBMA-like disease benefited from extra IGF1 genes in their muscle fibers
Note: “LIKE-disease” even if we dont have this disease… this wasnt the exact thing either but IGF1 helped
Nice one bud, 
Got tested for this this morning via an emg and nerve conduction test - which let me tell you is not pleasant (they stick needles in your muscles and move them around) and it was 100 percent normal.
Have you had any muscle loss/twitches?
Guys, do you know dutasteride is Kennedy Disease patients miracle drug?
Maybe we suffer something similar, in that andorgens/ dht are harmful for us ever since they returned when dropping finasteride
Post links to info regarding this to elaborate further please.
kennedysdisease.blogspot.com/2011/07/dutasteride-update-five-months.html
kennedysdisease.blogspot.com/2011/09/dutasteride-and-asc-j9-updates.html
ncbi.nlm.nih.gov/pubmed/21216197
Kennedy’s disease is completely different to PFS obviously, but i think it’s interesting because it is something to do with the androgen receptor and DHT is not good for these guys. Considering so many of us ‘crashed’ when DHT probably came flooding back, you never know, maybe it is harmful for us too? i am not trying to put forward a serious theory here, simply writing down some thoughts. I am most interested in there use of dutasteride.
I think Blase is onto something when he talks about DHT being pro inflammatory in some cases. The ‘crash’ event makes me think we had/ are having a bad reaction to DHT since we stopped suppressing it by 70% using finasteride.
“Spinal and bulbar muscular atrophy (SBMA) or Kennedy’s disease is a slowly progressive,
X-linked motor neuron disease for which there is currently no treatment. It is caused by a
mutation in the androgen receptor that results in a polyglutamine repeat expansion. Recent
animal studies have demonstrated that decreasing endogenous androgen levels leads to
functional improvement and increased survival. Studies have also shown that high levels of
5 alpha-reductase, the enzyme that converts testosterone to the more potent
dihydrotestosterone (DHT), are present in the ventral spinal cord, while low levels of this
enzyme are found within skeletal muscle. Thus, by selectively decreasing levels of DHT with
dutasteride, a 5 alpha-reductase inhibitor, it is hypothesized that there will be a
selective protection of motor neurons, without the adverse effects of reducing the anabolic
effects of androgen on muscle.”
I don’t know how long you guys want to ignore the fact that 5 AR inhibitors have in cases helped PFS. I certainly am not.
Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial
ncbi.nlm.nih.gov/pubmed/21216197
Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy
ncbi.nlm.nih.gov/pubmed/19259967
Followed by…
Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial (2010)
ncbi.nlm.nih.gov/pubmed/20691641
Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives.
ncbi.nlm.nih.gov/pubmed/15133611
There are some interesting similarities; ‘ligand-dependent toxicity’. But anti-androgens arent used for this condition and its not a miracle drug for them - even for the person in the blog.
Can I ask bluecloud87 aka Joe-91/Uk20/sanfran55/BaldyLocks to stop lying and trying to encourage continued use of Finasteide.
Anti androgens ARE used for this condition. Check the blog and you will see that a number of men have had very positive experiences from using Dutasteride. The term miracle drug was used rather loosely but it’s no surprise to see you taking it literally. I am not encouraging the use of 5 AR inhibitors; i am simply saying that they have helped some post finasteride sufferers. Which is a fact.
Crawl back into your little hole Oscar. Your what, 30 or something like that? and yet you are persistently bitter with people in the same dire situation as yourself. And revealing details and bald jokes? aren’t you balding and wasting away yourself? seriously, it’s about time you grew up mate.
If you think so why don’t you continue to take finasteride? Why aren’t you on it now?
No one is trying to deny the short honeymoon period you felt while retaking the drug. However other people feel directly worse when taking 5AR inhibitors. I think we’re all more concerned about the more serious, long-term sides after discontinuing use.
Provide a Link.
Provide a Link.
??? The blog and the study you have linked prove the exact opposite - it doesnt work. So what are you talking about?
No its not.
Havent you wasted years of your life posting thousands of message about your personal life all over Hairloss websites?
Havent you posted hundreds of pictures of your bald egg-head all over the web? (-Possibly more than any other human in history-)
Havent you constantly sought attention and sympathy on those websites like a total FREAK.
Now you turn up here, pretending to be ill? You’re one world-class wierdo Joe.
You have made 1000+ posts of total crap, dont invent stupid crap up just to make yourself more interesting
(p.s. Im 27)
The links are provided in the original post to Mew. I did use the hair loss forums a lot, yes. Coincidentally, i was using them when i began taking finasteride and became depressed because of the drug. The minute i took the stuff, my life spiraled downwards. I began to over analyze everything. PS I probably look a million times better than you bald. Oscar, you are blatantly a bitter loner that has been paying far too much attention to me. It would probably do you a world of good if you focus more on your own life.
Ok, there is nothing solid on 5 AR inhibitors helping us but they have helped a number of us and i just made a link with the kennedy’s disease patients using dutasteride and giving them there lives back. The links are right there 
There is no evidence I can find in the links you have provided or elsewhere of anti-androgens being a ‘miracle cure’ or ‘giving their lives back’ to men with Kennedy’s disease. Even the guy in the blog has no success. So, what are you talking about?!?
Joe, the only fool posting here about 5aR inhibitors helping IS YOU! No person truly suffering with these side-effects would ever dream of doing such a thing. Yet you claim to have already done so. Arent you just attention seeking here like you have done (for the last 5yrs) on hairloss sites?
I think everything you have ever posted is bullshite.
You must be missing something if you can’t see that the guys on that blog had big improvements using dutasteride. I don’t know what to tell you.
Yep, a lot of the stuff i have posted probably is bullshit. You have also posted 100% bullshit.
Dude, you think everything people post is bullshit as if it’s some conspiracy. I’m not trying to insult you, I’ve read your posts and a lot of what you say makes sense because you use studies to back up your thoughts and talk in a clear, concise matter. However, I really don’t think bluecloud is making up the fact that when he took a 5AR2 inhibitor, a lot of his sides cleared up. Yeah, he can sometimes post random things that he doesn’t know about (bluecloud, sometimes its true), but if he directly took a 5AR2 inhibitor and had success, there’s really not denying that, he actually took it and that was the effect.
I def. don’t recommend anyone take it, I def. wouldn’t touch that again, not sure why he did… but it’s another clue as to what’s going on.