Is there an association between isotretinoin therapy and adverse mood changes? A prospective study in a cohort of acne patients

isotretinoin
accutane
roaccutane
#1

This prospective study of Accutane/Isotretinoin and depression/mood disorders appears to capture what is really going on, with a small subset of the patients (3 of them, out of 56) developing psychological disturbances, along with severe physical symptoms during treatment, while the remainder responded favorably:

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