Interesting use of mRNA technology

The Penn team designed mRNAs that could turn regular T cells into therapeutic CAR-T cells inside the body to target heart fibrosis, a scarring from cardiac injury that impairs heart function. In a mouse model of heart failure, an injection of the therapy removed cells called activated fibroblasts, leading to a significant reduction of fibrosis and improvement in heart function.


It’s incredible how quickly this kind of tech is moving along.