Interesting article on the hormonal effects of overejaculation

Excessive sexual activity and over-ejaculation lead to overproduction of androgen hormones, causing adrenal and sex organ fatigue, and excess release of dopamine to maintain prolonged sexual arousal. Since dopamine is the precursor to the stress hormone epinephrine (adrenaline), excess dopamine results in the adrenal glands overproducing epinephrine and putting the body in a prolonged state of fight-or-flight stress. At the same time, norepinephrine is synthesized from dopamine and released from the adrenal medulla into the blood as a hormone, along with the stress hormone cortisol. Epinephrine, norepinephrine and cortisol fuel the fight-or-flight response, directly increasing heart rate, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle. All of this has a severely taxing effect on the body.

The hormone prostaglandin E-2, which serves an important function in sexual arousal, is also overproduced and has an inflammatory effect on the body, damaging tissues, nerves and joints, weakening immunity, causing muscular and nervous pain, and promoting infection, inflammation, and even cancer. Chronic elevation of epinephrine and prostaglandin E2 results in severe damage to brain cells and parasympathetic nerves in the liver, lungs, adrenal glands, heart, blood vessels, digestive system, pancreas, gallbladder, ovaries, uterus, cervix, testicles and prostate. As a result, you can experience a variety of symptoms, including depression, anxiety, bodily pains, vision problems, persistent sexual arousal and sexual dysfunction such as impotence and premature ejaculation in men and a lack of sexual stimulation in women.

All of this over-activity and stress causes the pituitary gland and testicles (ovaries in women) to become disabled for a few days or even months, leading to a long refraction time or a long-term sexual exhaustion and inflammation. First, you may feel your muscles and joints become very tight and rigid upon ejaculation. An extremely exhausted adrenal function can cause an extreme low level of DHEA and cortisol, resulting in fatigue and pains throughout the body, including the back. The pain becomes severe at about 2-4 hours after ejaculating due to the sudden drop of DHEA, testosterone and DHT. You may experience pains for a couple of days until your prolactin and cortisol levels are returned to their normal ranges.

In order to reverse the ill-effects of excessive sexual activity, over-masturbation, or over-ejaculation, stop sexual activity for a few weeks. Let your body rest and replenish. Then you can come back to it with a lower frequency. A healthy habit is to ejaculate a total of three to four times a week.

ViaPal-HGH-P, ArginOx and fish oil (1000 mg each meal) will help you gradually rejuvenate your neuro-endocrine function and boost your prostaglandin E-1/E-3, oxytocin and nitric oxide production for erection and orgasm. American ginseng and maca help to rejuvenate your entire body. Horny goat weed and yohimbe will help increase flood flow and nutrient absorption for a harder erection and better ejaculation control. Damiana and saw palmetto will heal your prostate, which is responsible for producing and releasing semen and which is most likely overworked with your excessive sexual activity or masturbation.

There are many alleged treatments for hair loss, but most fail to address a major underlying cause: a high stress physical response, sometimes triggered by over-ejaculation.

During puberty, boys maintain an extremely high level of testosterone and DHT without stress and are therefore able to achieve a full head of hair. As they age, men with a high level of DHT and stress lose their hairs. Stress and its induced inflammatory factors in the bloodstream deplete melatonin production during the night and heat up the blood, causing hair loss. At the same time, men with low testosterone lose their hair. So in short, high levels of DHT and stress hormones and low levels of testosterone lead to hair loss.

Over-ejaculation triggers excessive testosterone-DHT conversion in the prostate and testicles, leading to a stressful fight-or-flight state in the body. In this stressful state, the body produces high levels of cortisol, which induces high levels of prolactin and reduces DHEA, HGH and testosterone production. At the same time, excessive prolactin and epinephrine induces constriction of the arteries, leading to poor blood circulation everywhere in your body, particularly in the scalp and prostate. All of this contributes to hair loss.

A 2001 study examined the effect of a 3-week period of sexual abstinence followed by masturbation-induced orgasm. It found that abstinence over such periods “does not change the neuroendocrine response to orgasm but does produce elevated levels of testosterone in males.” A 2003 study showed that serum testosterone levels reach a peak seven days after abstaining from ejaculation. In short, the findings mean that excessive sex results in adrenal and testicular fatigue, leading to low testosterone level and hair loss.

In addition, exposure to stress and steroid-related toxins are likely to increase the activity of 5-alpha reductase for greater testosterone-DHT conversion. Excessive amounts of the amino acid L-arginine in conjunction with a high level of androgen hormone can over-excite the nervous system for excessive testosterone-DHT conversion, triggering a stress response.

To rejuvenate your nervous function for libido and reduce the epinephrine release from the hypothalamus, brain stem and adrenal medulla, supplement with ViaPal-hGH-J (or ViaPal-hGH-P if you are over 30), 5-HTP, DeToxiA, fish oil, borage oil, calcium, magnesium, and Vitamin-D. In addition, GABA can reduce oxytocin synthesis, limiting the stress response. Nitric oxide and cGMP reduce constriction in the arteries, improving blood circulation to the scalp and prostate. American ginseng and maca help to rejuvenate your entire body. Damiana and saw palmetto will heal your prostate, which is responsible for producing and releasing semen and which is most likely overworked with your excessive sexual activity or masturbation.

Acne is caused by a number of factors, including diet, stress, accumulation of dead skin cells, bacteria in the pores, use of steroids, poor hygiene, drugs and medication. In addition, acne can be caused by over-ejaculation.

Excessive sex and masturbation can increase histamine, the super hormone DHT, the stress neurohormone epinephrine, and the inflammatory hormone prostaglandin E2 to induce acne outbreak. This sympathetic nervous action on the cells is exacerbated by a number of factors that can trigger the skin’s neuro-endocrine function, leading to acne. Those factors include exposing the skin to heat or sunlight, excessive sex, stress, insufficient sleep, eating inflammatory foods – especially those high in Omega 6 fatty acids – and consuming caffeine.

There are a number of treatments for acne. Medications can be effective in the short term, but they fail to address the underlying medical conditions causing acne. Proper hygiene is always important in keeping the skin clear of dead cells and bacteria. In addition, PinealTonin will reduce the release of epinephrine, histamine, and prostaglandin E2, thus reducing the chemicals vital to acne growth. Tea Tree Oil has been shown to be an effective anti-inflammatory in skin infections. American ginseng and maca help to rejuvenate your entire body. Damiana and saw palmetto will heal your prostate, which is responsible for producing and releasing semen and which is most likely overworked with your excessive sexual activity or masturbation.

Check these out. Scary how similar they are to PFS…

cure-erectile-dysfunction.org/symptoms-of-sexual-exhaustion

Sexual exhaustion is complete internet bullshit conspiracy if you ask me, i don’t know why you are even looking into this. I would often have sex up to 8 times in a day before finasteride and i had no persistent issues.

what about this theory?

limitationsnooneseemstoaccept.wordpress.com/2010/10/06/post-finasteride-syndrom-could-be-a-xmrv-related-chronic-disease/

i guess this one is very angry with our forum :mrgreen:

The theories behind XMRV were recently discovered to be scientifically flawed. As the current wisdom stands, it is very unlikely that XMRV exists in humans and the human specimens tested positive due to contamination in the laboratory.

I have also previously been intrigued by the idea of sexual exhaustion since the symptoms very closely mirror PFS. However, the research and foundations of the idea seem to be very dubious to me at this point. To be fair though, I did catch a glimpse of PropeciaHelp in 2008 at which point I felt it seemed illegitimate and decided to give the drug a try. If you look at the forums for sexual exhaustion, it seems to be only a few guys who have no success in treating their problems.

Overall, I think a lot of these proposals seem completely logical at first glimpse (sexual exhaustion, XMRV, prostatitis) but really don’t seem to match with scientific observation. As somebody without a medical background, I find it very difficult to determine which types of evidence and theories to weight heavily in my research and search for a cure versus which should be rapidly discarded.

PS - I would be pretty interested to hear what others think of the sexual exhaustion hypothesis since I haven’t fully ruled it out but I am skeptical. What does not make sense is that this approach would prescribe abstaining from sexual activity for months in order to attempt a recovery. Of note: When I first developed problems, I almost completely quit masturbating for about 2 months and experienced no rebound during this period.

This basically has a lot of the same premises as PFS it appears, as if PFS induces sexual exhaustion as the body cannot recover with the disrupted hormone stream. However as healthy, young males nobody should be experiencing this.

+1

Dr. Lin isn’t the most credible source. He’s an engineer by training and a supplement vendor by trade.

any source for your posts?
are you musalman? I think you are musalman.
your way of writing resembles a lot to that of musalman’s and he was constantly talking like that.
I know musalman was banned from Musclechatroom.com and then he rejoined the forum few times under different names like “Suffering” so maybe you are doing the same thing over here.
After all what is the purpose of writing this all here? This is more relevant to general fatigue , debility issues.

Thought that maybe I should post a PM I got from a member who used to post here a lot since it relates to this thread. He thought that our problems were related to “sexual exaustion” or whatever you want to call it. I sent him asking how he was lately since I knew he had planned on testing the theory about SE…here is his reply.

I also asked him to reply back to me or post a recovered thread here when he gets a chance, giving us more details. This was 4 days ago…maybe he will show up again.

What does this mean? He is claiming a recovery merely from abstaining from sexual activity?

now recovery from stopping sex?. I have got an idea that will guarantee 100% recovery. cut off your penis,no sex no worry and life full of colors.
guys come on please! there are enough funny theories around. Please give us a break.

There was a time for about 2-3 weeks were I was completely impotent. After that long down time I did feel better and improved sexually somewhat. Nothing compared to pre Fin days of course but compared to crash was an improvement, maybe 60-70% of normal.

Here is his latest PM.

[i]In regards to recovery, what I’ve learned is that anything that is not performed in moderation will come back to bite you. Whether its drugs, alcohol, or sex – if any of these are abused and used excessively, or you have intrusive thoughts about them constantly, there will be a problem.

In order to recover my sex drive, I had to examine my life very closely. I monitor my thoughts daily, even hourly, to see if I am thinking negatively, or if I am uneasy, or unhappy in any way – then I ask myself why I feel that way – the answer is always “I have chosen to feel this way or react this way to whatever is happening in my life”.

See, anytime I grew bored, uneasy, unsatisfied with anything, I would turn to porn to shut off my mind and to numb my thoughts. Eventually, this became my only way of coping with life, for 15 years now. Correspondingly, my sex drive plummeted because porn is highly addicting and over-simulating, thus blunting my sex drive and arousal. I abused it, used it in excess, and it became a problem that I didnt recognize till years after my sex drive diminished.

Now I must make time DAILY, to listen to self-help audiobooks (For example, “Tony Robbins - Personal Power”, or “Eckhart Tolle - The Power of Now”) , re-examine my emotions, do breathing exercises, get invovled again with my old hobbies that I dropped (singing, guitar, piano, website building, basketball, etc), in order to balance my life and to quiet my intrusive thoughts.

It has not been easy. You will feel powerful motivations on somedays, but then utter despair on other days. I still fall back into my old ways if I do not monitor myself closely and daily.

My sex drive is still not 100% back, but it is like 75% better than it was last year. I know that it is directly tied to my ability to cope with stress.

I hope that helps. Please avoid the steroid cream, it can cause you some serious problems. I did not use any external dietary supplements whatsoever, it was entirely mental for me. I denied that it was mental for many years…the subconscious mind is a powerful thing.[/i]

Good for him, glad he found the source of his issues. Unfortunately, there is no way to “think” your way out of a shrunken penis, gyno, or low Testosterone.

The vast majority of men suffering from persistent Finasteride side effects are dealing with real physical, neurological and hormonal ramifications that has nothing to do with porn addiction or suggestive thoughts.