The insensitive and gummy skin is due to the lack of nitric oxide?
According to this article, yes! let’s try to increase it!
Sensory information from the eyes, skin or ears goes first to the thalamus, which acts like a gateway and either allows the information to flow on to the cortex, the thinking part of the brain, or stops it. Scientists knew that the thalamus sends information to the cortex, but did not know that nitric oxide affects how the cortex communicates back.
“What we have shown is that nitric oxide released into the thalamus enhances communication between the thalamus and cortex. This is a whole new understanding of how the brain communicates,” said Godwin.
He explained that the cortex receives visual information from the thalamus that is basically just a small part of an image, analogous to a pixel in a photograph. The cortex then builds up a more complex representation, which it then feeds back to the thalamus to select the information that it needs to complete or organize the picture. Nitric oxide enhances this feedback effect.