Importance of inhibin B in the regulation of FSH secretion in the human male.

Very nearly every single case of PFS exhibit low FSH (3.0 MIU/ml or lower) regardless of testosterone status - normal is 5.1 or 5.5, with standard deviation of 0.7 or 1.2, respectively, depending upon the study . My own Inhibin B has always come back abnormally high (240, 400+, etc.). Perhaps this paper will convince more to be tested and see if we can identify elevated inhibin as another common factor (like Adiol-G). kazman

my inhibin b is well within range…

golf,

Well within what range? That stated by the blood test lab? Those ranges tend to be overly broad due to the test’s use in suspected cases of lead poisoning.

Doctors that use inhibin B clinically tend to have their own specific ranges. For example, an inhibin B of 80 indicates infertility, while a range of 140 to 180 pg/ml is considered normal.

What is your FSH level?

Thanks -

Mines too high - 9.0.

Kazman, have you ever has a spermogram done?

I spoke to Professor Bouloux (As you know) about FSH/inhibin B and he said there is a very close connection between the two. From what i gathered inhibin B is much more important in healthy sperm production than FSH. I told him in had FSH levels around 2-3 and he said that that was completely normal and that if anything that would indicate a higher inhibin B level which would probably mean i have “dynamite” in my semen. Note, i have healthy testosterone levels etc though - that was bourne in mind when we made those “conclusions”

That said, im not entirely convinced that my fertility is off the charts. I’d be pleased if it’s within normal range (i’d imagine its lower than optimal but acceptable). I haven’t had a spermogram to test any of this, though.

i actually cant find my inhibin B right now, but i’m fertile. the only abnormal thing about semen was low volume.

why this thread died?

Not more watery or anything?