That is late! Get your rest friend 
I have lost the fat under my eyes and face people continue to tell me I have lost weight. Also if you wouldn’t mind filling the survey out please that would be awesome, it’s very important if we are to get to the bottom of this.
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I hope eye issues are officially investigated sometime in the near future, it seems a strong potential source to learn more about what PFS is. My eye changes are the most tangible out of all my PFS symptoms - ptosis (lower eyelid has dropped and upper eyelid is drooping, more extreme on one side) constant ‘dry eyes’ that barely respond to eye drops darkness/thinning out underneath and frequent inflammation of the sclera.
Hi. How/where do i fill out the survey?
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The survey can be accessed through the bar-graph icon at the top of your screen it can be halted at any time and continued at a later time/date.
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Thanks for signing up @Maischel, I don’t have advice for you I’m afraid, but please be careful with the advice you take. We have a history of someone here with skin problems taking advice and dramatically worsening his symptoms. I am sorry to not have good news for you, but I’d strongly suggest you get behind any projects here and help us get to the point where we understand what’s happening and safe treatment can be sought.
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I hope so too. The eye Problems are the most obvious symptom i guess.
I have filled out the survey now!
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Good man 
If you want you can get a dermatologist to put filler under your eyes to completely replace any fat loss. Just letting you know about that option in case you just want to look better. It’s one of the most common aesthetic procedures since it is one of the first signs of aging and easy to reverse with filler.
Hi. Thanks for the suggestion. So far as i know, those fillers are just temporary. That is a big problem to me. I am 20 years old. I really dont want to do surgery again and again for the rest of my life. I read quiete a bit about that. There are a lot of horror storys about that (that it looked like shit after the surgery , that the fat/creme disappeared very fast after surgery, etc.).
I hope that there is another option. I think a Main problem is, that it isnt possible to contact a people in this forum anymore, who wrote about same problems with there eyes. Maybe someone figured out a solution or theirs eyes recured by it self a bit.
Sorry for my bad english. I hope you can understand me.
-Maischel
I’m not talking about surgery. I’m talking about injections that take 5 minutes once every 6 months for fillers that dissolve quickly and once every couple years for fillers that last longer.
Okay. Thanks for clearing that up for me. But nevertheless i dont want to go to get injections under my eyes every couple of months/years. The eye-area is by far not my only problem. Like i mentioned, my face looks just fuc*ing bloated. My brother told me the last time i saw him that i am looking like a guy, who is working at least 40 hours the week and sleeps 5 hours every night (although i am 20 years old and live a relaxed and healthy life).
I am sure that i can beat my skin and health problems (except for the lost eye fat probably). A few months ago a doctor diagnosed a little thyroid subfunction and i dont want to get any kind of chemical hormones into my system. The fact that a few people here cured from their post finasteride syndrom gives me the hope, that i can get there too. Without injections, hard medications, etc.
Androgens play a large role in collagen content of the skin.
This is one of the worst sides I have gotten, proportionally. When my libido gets better so does my skin so It’s 100% an androgen receptor issue.
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You need fillers to replace the missing collagen or use an LED mask as an ongoing treatment. The best is Opera which retails around £1900. Best to see a skin beauty therapist for a list of options.
Fat transfer surgery is the closest permanent option for sunken eyes costs £3-5k.
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@Maischel I get sunken eyes “the morning after”, along with deep physical and mental exhaustion. It lasts for 24-36 hours. In other words, I need two nights of sleep to fully recover.
I have tried drinking a lot of water beforehand, taking ibuprofen, getting a lot of sleep… nothing seems to help. At least my eyes are not like that all the time. Once I get rest, my eyes come back to looking fairly normal. For you, is it all the time? Does it change under any conditions?
I think so too.
Yes it does. Not much but it does. A week ago, i was fasting for 3 days. My skin looked so much better, my face didnt look much bloated anymore and my eyes were on the way back to normality (). But now it is worse again.
After two years i think that ive found out what causes my problems. I am pretty sure that i got high cortisol levels. It really fits with all my symptoms (bloated face, oily skin, thin skin, especially under the eyes, brain fog). The skin, bloated face etc. is not every day the same. The fasting showed me in a very impressive way that it ts possible for me to go back to normal.
Almost two years ago i already had the idea with the increased cortisol level. I did go to a doctor to make a blood sample. In fact my cortisol levels where a bit elevated. The main problem was that my doctor didnt believe that i have cushing-syndrome. I also dont think that ive got the cushing syndrome. For example because i am able to build muscle mass. That was the main reason why i gave the idea for the cortisol-theory up. But the symptoms ive got are very similar and fit right into the cushing-syndrome and in general to high cortisol levels.
And now i am damn sure that this is the cause for my problems. I am also pretty sure that high cortisol levels are not the main cause for all sunken eye victims of propecia.
So the last days i did much research and i am trying to find a way to reduce my cortisol levels. I really would like to do another fast (i did a green-smoothie-fast btw.) but i think i am phisically not in the condition to do so right now.
the thing is that i can really feel when my cortisol level increases: that is almost every single time after eating something. Also in stress situations, mostly after going to the gym (on cardio not that much, sometimes it feels even good for my stress level).
In all situations that stress me out, my face looks puffy pretty quickly. My skin turns reddish and my eyes look pretty smacked. Because of the short-term success I had with smoothie fasting, I am now very sure.
I already found a few threads to the connection of finasteride and high cortisol levels in this forum but until now nothing mind breaking.
See these papers:
- Nasiri et al (2015). 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes
https://www.ncbi.nlm.nih.gov/pubmed/25974403
pharmacological inhibition using the 5α-reductase inhibitors finasteride and dutasteride augmented cortisol action
- From some of the same authors:
Hazlehurst et al (2016). Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man.
https://www.ncbi.nlm.nih.gov/pubmed/26574953
5α-Reductase 1 and 2 (SRD5A1, SRD5A2) inactivate cortisol to 5α-dihydrocortisol in addition to their role in the generation of DHT
Thanks!