Hey guys. I posted that masturbating 4 times a day was improving my PFS and that NoFap caused my PFS.
The hypothalamus is a small but important area in the center of the brain. It plays an important role in hormone production and helps to stimulate many important processes in the body and is located in the brain, between the pituitary gland and thalamus.
When the hypothalamus is not working properly, it can cause problems in the body that lead to a wide range of rare disorders. Maintaining hypothalamic health is vital because of this.
The hypothalamus acts as the connector between the endocrine and nervous systems to achieve this. It plays a part in many essential functions of the body such as:
- body temperature
- thirst
- appetite and weight control
- emotions
- sleep cycles
- sex drive
- childbirth
- blood pressure and heart rate
- production of digestive juices
- balancing bodily fluids
Hormones secreted by the hypothalamus include:
- antidiuretic hormone, which increases how much water is absorbed into the blood by the kidneys
- corticotropin-releasing hormone, which helps regulate metabolism and immune response by working with the pituitary gland and adrenal gland to release certain steroids
- gonadotropin-releasing hormone, which instructs the pituitary gland to release more hormones that keep the sexual organs working
- oxytocin, a hormone involved in several processes, including the release of a mother’s breast milk, moderating body temperature, and regulating sleep cycles
- prolactin-controlling hormones, which tell the pituitary gland to either start or stop breast milk production in lactating mothers
- thyrotropin-releasing hormone activates the thyroid, which releases the hormones that regulate metabolism, energy levels, and developmental growth
Symptoms:
- sensitivity to heat
- anxiety
- feeling irritable
- mood swings
- tiredness and difficulty sleeping
- lack of sex drive
- diarrhea
- constant thirst
- itchiness
NoFap increases Androgen Receptor Sensitivity and I thought that’s what caused my PFS but apparently NoFap also has a big affect on Hypholamus and I think that is what is the cause of PFS and explains why masturbating 4 times a day works for me.
Finasteride affects Hypholamus:
The effects of FIN on FST responses were associated with a dramatic decrease in corticotropin release hormone (CRH) mRNA and adrenocorticotropic hormone (ACTH) levels. These results suggest that FIN impairs stress reactivity and reduces behavioral activation and impulsive behavior by altering the function of the hypothalamus–pituitary–adrenal (HPA) axis.
I said that when I took the SSRI, Citalaprom, I felt cured of all my PFS symptoms but it stopped working when I tried it again. Citalprom affects Hypholamus:
Serotonin re-uptake inhibitors (SSRIs) can affect the basal activity of the hypothalamic–pituitary–adrenal (HPA) axis in rats. A single injection of citalopram has been shown to stimulate the HPA axis while repeated administration leads to attenuation of the corticosterone response to the SSRI.
I said after I started taking Curcurmin it improved my erectile dysfunction and penis shrinkage. It affects Hypholamus:
We hypothesized that curcumin may also alleviate stress-induced depressive-like behaviors and hypothalamic-pituitary-adrenal (HPA) axis dysfunction.
These results provide compelling evidence that the behavioral effects of curcumin in chronically stressed animals, and by extension humans, may be related to their modulating effects on the HPA axis and neurotrophin factor expressions.
I said Green Tea improved my PFS symptoms and helped with hair regrowth: It affects Hyphomaus:
The results showed that dietary supplementation with matcha could effectively inhibit the weight gain, fat accumulation, glycemia and lipidemia increase, and excessive activation of microglia in the arcuate nucleus of the hypothalamus.
I said after I took CBD Oil I had huge erections. It affects Hypholamus:
CBD and other cannabinoids may restore balance to this system directly through the hypothalamus and pituitary but also on the endocrine organs themselves.
I always saw people say they were cured of PFS when they used Tribulus and I was really confused because I read that Tribulus can upregulate Androgen Receptors. Now I see why it works for PFS. It affects Hypholamus:
Objectives: To study the effect of acute and repeated dose administration of lyophilized aqueous extract of the dried fruits of Tribulus terrestris (LAET) on sexual function in sexually sluggish male albino rats.
Materials and methods: Aphrodisiac activity of the test drug was evaluated in terms of exhibited sexual behavior. In order to assess the effect of chronic T. terrestris exposure on the hypothalamus–pituitary–gonadal axis, testosterone level estimation and sperm count were carried out. Twenty-eight-day oral toxicity studies were carried out to evaluate the long-term effects of the LAET administration on different body systems.
Results: A dose-dependent improvement in sexual behavior was observed with the LAET treatment as characterized by an increase in mount frequency, intromission frequency, and penile erection index, as well as a decrease in mount latency, intromission latency, and ejaculatory latency. The enhancement of sexual behavior was more prominent on chronic administration of LAET. Chronic administration of LAET produced a significant increase in serum testosterone levels with no significant effect on the sperm count. No overt body system dysfunctions were observed in 28-day oral toxicity study.
I said that I think Androgen Receptors in the brain have a lot to do with PFS and you guessed it:
The hypothalamus, preoptic area and brain cortex were found to possess a single class of high affinity binding sites for androgens and the dissociation constants
https://www.sciencedirect.com/science/article/abs/pii/0039128X76900945
I said that masturbating 4 times a day really started improving my PFS symptoms and I felt so much better: It affects Hypothalamus.
Male sexual behavior is regulated by limbic areas like the medial preoptic nucleus (MPN), the bed nucleus of the stria terminalis (BST), the nucleus accumbens (nAcc) and the ventromedial hypothalamic nucleus (VMN). Neurons in these brain areas are rich in androgen receptors (AR) and express FOS-immunoreactivity in response to mating. In many species sexual satiation, a state of sexual behavior inhibition, is attained after multiple ejaculations. The mechanisms underlying sexual satiation are largely unknown. In this study we show that sexual activity reduces androgen receptor immunoreactivity (AR-ir) in some of the brain areas associated with the control of male sexual behavior, but not in others. Thus, one ejaculation reduced the AR-ir in the MPN and nAcc, but not in the BST and VMN. Copulation to satiation, on the other hand, reduced AR-ir in the MPN, nAcc and VMN, and not in the BST.
When researching I read about Gonadotrophin, which is affected after starting NoFap.
Gonadotrophin-releasing hormone is produced and secreted by specialised nerve cells in the hypothalamus of the brain. It is released into tiny blood vessels that carry this hormone from the brain to the pituitary gland, where it stimulates the production of two more hormones – follicle stimulating hormone and luteinising hormone. These hormones are released into the general circulation and act on the testes and ovaries to initiate and maintain their reproductive functions. Follicle stimulating hormone and luteinising hormone control the levels of hormones produced by the testes and ovaries (such as testosterone, oestradiol and progesterone), and are important in controlling the production of sperm in men and the maturation and release of an egg during each menstrual cycle in women.
Any trauma or damage to the hypothalamus can also cause a loss of gonadotrophin-releasing hormone secretion, which will stop the normal production of follicle stimulating hormone and luteinising hormone, causing loss of menstrual cycles (amenorrhoea) in women, loss of sperm production in men, and loss of production of hormones from the testes and ovaries.
I think that is what caused PFS. It all make senses to me and explains why all those things I tried work for me. I read about adrenaline fatigue and all the symptoms seemed similar to PFS symptoms and HPA Axis Dysfunction (Hypholamus) and adrenaline fatigue are one in the same. This is really a breakthrough for me and hopefully it can help a lot of people suffering from this disease. God is good! Allahu Akbar!