High Fat Diet causes leaky gut

@ozeph
I admire your tenacity… I hope to one day reach your level of recovery… I’m not trying to act smart im just trying to figure this out. I saw a video that says if you reach a certain point in ketosis it can completely reduce inflammation. I will find it for you now.

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I have no doubt about this. I’m 53yo and I have no joint pain at all, didn’t have a headache since I’m on this diet (compared to 5 complete days a week of constant headaches before). I didn’t catch a single cold, flu, virus or whatever and I didn’t get a single mosquito bite for 2 1/2 years (and my house has lots of mosquitos, everybody gets bitten). I don’t even get bruises anymore, which means my blood vessels are more elastic.

And your right about our guts. Most have bacterial imbalances in the guts and that can cause inflammation and leaky guts so yeah, it’s definitely good to consider probiotics and get the guts biome properly balanced if our disease will let us do that (?!?)

I had a long discussion on the subject. We’ve got polyglutamic toxicity because of epigenetically dysfunctional androgen receptors from what I understand. That explains low GABA and insomnia, and probably why bifidus strands (normally 90% of guts biome) have been said to not be present in PFS sufferers.

But addressing the symptoms of epigenetically dysfunctional androgen receptors does not fix them. Taking bifidus doesn’t necessarily mean they’ll stay alive. The only solution I found was to address directly the epigenetic damage by researching what repairs the epigenome. And that’s what I’m doing. Let’s wait another 3 years and we’ll see if my approach is sound.

That video explains it well !

there was a user on here that never took finasteride, but attributed his symptoms to a change in diet. bascially he went keto and developed numb genitals…

I understand. I’m not taking it bad. To be honest, I’m worried being on such an extreme diet for so long could have bad effects on my liver or my cholesterol or something else. But I’m stuck between a rock and a hard place. The diet makes my life easier than if I try to stop it. And I tried stopping so I know !

This is why I say find what is best for you. Others have had success with this diet so there must be something to it !

Lots of things can damage the epigenome as to make it dysfunctional. a stressful boss, a bad relationship, working with chemicals etc…

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why dont we look directly into the gut, and try to reach a consensus…

for example, get 15-20 guys to check for things like Calprotectin, Zonulin, and compare results…
We can see if there is a trend. We can compare bacteria etc…

One guy cured by treating SIBO, Chi also said its because of overgrowth of “normal” bacteria in the gut.

You can try that. Personally, I’m done trying to fight this disease. I’m at cruise speed and the diet and lifestyle is so great I will not stop it even if I’m cured.
Right now my research are in economics.

It’s a good idea ! I would suggest you try with yourself and if you can get others onboard, please share your results !

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Any update or suggestions on how to fix this Ozeph? My GABA is heavily dysregulated. Symptoms include feeling wired, overstimulated, hyperaroused, etc.

What type of foods do you advocate for in your style diet model? I have high amounts of D-Latate producing bacteria in my stool test, my gut microbiome profile is of that with someone with CFS/ME, apparently these bacteria feed on sugars / carbohydrates so I’m planning to experiment with a zero carb diet model.

Appreciate any advice you may have, thanks.

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Hi @Alex50

If your serious in pursuing this path in trying to alleviate your PFS symptoms, please try to test for Zonulin, and Calprotectin as well!

Zonulin elevated can indicate leaky gut, and calprotectin can indicate gut inflammation.

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Thanks, I will do the next time I get a stool test. I had zero mucous or blood in my stool, so this is a good sign of minimal gut inflammation, but I will be sure to get a more comprehensive analysis done with Zonulin and Calprotectin done next time.

Avoid all things with GL: Glutamine, monosodium Glutamate, Glycine, and most of all: Glucose which will come from any carbs.

I suggest a ketogenic diet as it lowers overall stress and is renowned to make people more calm. Some have tried it and slept better.

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Well if a person was to cut out carbs and cut out fat, low dairy, and red meat whats left to eat?
I would a agree with refined sugars or empty carbs being a bad thing, like in soda.
I believe the right carbs though just like healthy fats can be part of a healthy diet.

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@guitarman01

I guess this kind of stuff is specific to every individual. I myself have an overgrowth of Bilophila Wadsworthia which is linked to Intestinal inflammation and associated with High fat animal diets. Which is basically what I ate when I got wrecked.

yes I would swing more towards a low fat diet then a low carb diet myself. Also low-fat dairy. A person can get plenty of healthy fat just eating a handful of nuts.
The worst diet is of course is the westernized one, which is a good reference of what not to eat.

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I think this whole issue does not have the same source for everyone. Different bacteria, different food allergies, different causes of inflammation. It’s why it requires a tailored approach to each and every individual. Eating eggs maybe bad for one person (allergy) but be beneficial for another for selenium etc…

Where do you go about getting these tests? Happily do it if it gives you a data point

Try to get your doctor to do these tests, if not you will have to do them privately as I did here in Europe.