Ok I have been taking Dostinex (Cabergoline) for more than 4 months now, because I had to. Last week my glandular Gynecomastia was acceptable compared to what it was before. However I stopped Dostinex in the same week. Now, one week after the withdrawal, gyne is flaring up, gladular breast tissue is spreading very fast. I still didn’t test for prolactin level after the suspension. I don’t know what to do, I don’t want to continue taking Dostinex, I’m sick of drugs. And what is it worth for if Prolactin raises as I stop Cabergoline? My estrogens are ok in the lower range, prolactin is probably high, T is quite surely low near the lowest limit. Not sure about the T/E ratio however.
Any suggestion? thanks.
I have similar problem. High prolactin and estrogen. I don’t have any medical knowledge to give you any advice, i can only tell what i am going to do. I will, again, include tribulus to my regime, cause i had 2-3 periods lasting couple of days when i felt almost fully recovered. I just recently understood that most probably bromocriptine and tribulus were responsible for that.
It is strange to me that you have gyno with low estrogen. Also, maybe your progesterone is low. In my case, (my opinion is) that both, low progesterone and high prolactin are caused by high estrogen. So without reducing estrogen/increasing testosterone you can’t ( in long-term) reduce prolactin.
I had gyno issues the past few years even when my e2 was mid range. I had to take huge doses of arimidex to stop the gyno and it pushed my e2 wayyyy low.
Started taking pregnenolone 100mg twice a day about 10 days ago and so far it has stopped the gyno, even without arimidex.
I recall my prolactin was near the tumor limit. Not exactly a mild hyperprolactinemia.
Also during finasteride use I was surely hyperestrogenic.
Gyne might be due to an altered T/E ratio I suppose. Both my T and E are low. If E was low and T high, that would be a strange condition for gyne. However the fact that they are both low may explain the problem…I don’t know.
Will reply more precisely soon on the other points.
@tab:
Yes, that probably explains it.
@moonman:
Can you tell have you experienced some more benefits from pregnenolone? I have considered taking it, mostly to reduce anxiety, but i haven’t used it yet.
Johnny5ar, I am in accordance with your views about estrogens inducing hyperprolactinemia. Don’t know about progesterone however. My values were the following in January (under Dostinex)
Prolactin 0,19 ng/mL (2,64-13,13)
Testosterone 4,85 ng/mL (2,80-11)
Estradiol 32 pg/mL (25-107)
Progesterone 0,10 ng/mL (0,1-0,2)
Now that I’m off Dostinex, my T will be lower probably.
It is to be mentioned that at the conference on neurosteroids, it was mentioned that Finasteride induces a reduction in dopamine. So I don’t know if prolactin is related to estrogens entirely in our case.
How are you going to manage the estrogen?
moonman1
- You had midrange Estrogen; where was your T?
- Do you mean pregnenolone completely made the gyno regress?
How do you calculate the T/E ratio? and what is a decent range?
Well, high estrogen is also only a consequence. So, my current plan, which, i have to admit, doesn’t seem very promising (but might be of some help), is to increase testosterone with tribulus ( my testosterone was 21.6 ( 8.2- 34.8) few months ago) and to increase 5ar with nystatin. But the problem is that i have difficulties to find nystatin so i am only taking 500 000 pill per day.
Also, i have been taking vitamin c to increase progesterone for about a week, but haven’t noticed much improvements so far.
Haven’t used any anti estrogen so far because it will only temporarily affect one of many consequences of “root cause” which i believe, is not so mysterious in my case- low 5ar and its metabolites. And if that is the case, then resolving that will normalize estrogen i suppose.