Growth Hormone Insensitivity a similar disease?

General Discussion
#1
4 Likes
#2

Nice find! Seems similar on the surface. We can still produce hormones, but don’t respond to them just like those patients.

2 Likes
#3
1 Like
#4

It seems like this condition is the closest we have to PFS only different mutations at play.

#5

“One of the major findings of our previous study was the high prevalence of GHIS patients with normal levels of GHBP (27). The frequency of the GHBP-positive phenotype remains essentially unchanged in this larger cohort, emphasizing that suspected GHIS should not be excluded on the basis of normal GHBP.“

#7

@Dubya_B @awor @axolotl @Tzinkman
What are your thoughts on this can see you see any characteristics here that are similar with our own condition?

#8

I’m not seeing it. The symptoms are completely different and the underlying causes described are all mutations.

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#9

Thanks for the reply. I’m talking talking about it being a receptor issue at the heart of the problem and them not responding to growth hormones even when being administered much like ourselves only with Testosterone and DHT. Of course inherited mutations and epimutations are much different