So with this syndrome the liver sucks at metabolising, because some of the enzymes are not expressed enough. Perhaps one of them is responsible for finasteride also?
How many of us have hyperbilirubinema and are jaundice (plus maybe feel tired all the time)?
Apparently I too have Gilbert’s syndrome
Althought I never had a diagnosis I probably had Gilbert’s syndrome before finasteride. Becuase sometimes my eyes were yellowish especially when I drank alcohol. Also I’ve never been all that energized guy. I am not all that sure however.
I read some month ago that apparently Gilbert’s syndrome can prolonge one’s life. If confirmed, this wouldn’t be all that bad.
Of course you had it before finasteride. It’s a hereditary disease. And yes, as bilirubin is an antioxidant, it protects you, but it is still somewhat toxic. The pros outweigh the cons, though, I think, so keep positive 
!
I meant I never had my bilirubin checked until now and high unconjugated bilirubin doesn’t necessary mean you have Gilbert’s Syndrome. So I don’t know If I have GS, but it probably is the case. Otherwise, Finasteride may have had a role into this…maybe. This considering I had tremendous digestion problems while taking that stupid drug which was meant to be about “the safest ever known” 
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You should find out what the case is. High bilirubin isn’t anything to joke with, actually. G6PD deficiency can easily cause it as well and you may want to be aware of it, if you have it.
Thank you. mmm I asked my parents and actually they do not have high bilirubin. May this be normal if I have Gilbert’s syndrome? In any case I will follow your suggestion. You know I went to many doctors recently, spent lots of money, and all of them told me it probably was Gilbert’s syndrome. They do not took the time to say I should investigate this condition.
They had to do blood tests, if they saw you’re jaundice. Didn’t they do anything? It’s not like it’s too expensive. Depends on where you live, of course. Perhaps you have a really fucked up medicine system.
They probably did all the tests and the only noticeable thing was high bilirubin – therefore no hemolysis, no poikilocytosis, no liver infections. The only thing left then is Gilbert’s, so don’t worry.
I didn’t go to an hepatologist, because I had many other visits, and this would have probably meant another 100 bucks. My hormones are a mess so endocrinologists and uro/andrologists didn’t focus on bilirubin. They just said it probably was Gilbert’s syndrome, and i trusted them. I do not have clear jaundice, not usually. My last exam reported more than twice the normal level of indirect bilirubin and direct bilirubin at the upper limit. In fact I done lots of exams of general health, and apart from bilirubin, autoimmune thyroiditis, “very” high prolactin, hypogonadism and some other value being out of range, (LOL) everything seemed somewhat ok. But well, who knows maybe there are other exams to make.
Private visit or not, I do not suggest being cured in italy. Most doctors act as if they don’t give a shit. Paradoxically, you will have better attention if you go through the national sanitary system, which is cheap, but it normally takes quite a lot of time to have a visit.
I and others are in fact astonished by the fact that some research on PFS is being done in italy. There is a responsibility behind this though.
You don’t need a hepatologist to test for Hep A, B and C antibodies, haptoglobin, reticulocyte count, Hb, Ht and stuff like that. It’s common and very routine, so it’s done by your family doctor.
Well, ehm, I think I can trust better an hepatologist. You know I study science stuff and I am somewhat finicking on some questions. If i do not meet a similar attitude in my doctor, I go home and I am not all that convinced. Ok thank you for your advices.
About your original question, I cannot answer obviously. What I can say you is that while on Finasteride I had tremendous flatulence (did you experience this too?). After withdrawal the condition got really better. Now that I am on Dostinex, flatulence returned somewhat, but not at that extreme intensity.
I say it just because this is related to the digestion apparatus. But in my knowledge this might be due to the nervous system too (I had extreme anxiety). So honestly I don’t have answers for the moment.
No flatulence for me.
I got my last blood results and they say:
Total Bilirubin 2.50 mg/dl (0.1-1) 2.5 times the mazimum limit
Direct Bilirubin 0.6 mg/dl (0.05-0.3) Twice the maximum limit
Indirect Bilirubin 1.90 mg/dl (0.2-0.8) More than twice the maximum limit
I will indeed talk to my doctor soon and eventually to an hepatologist. In older tests I already saw high fractions of bilirubin, but these reads are far higher. I don’t drink it anymore that it’s Gilbert’s Syndrome. Both fractions are high, so there is something wrong. On this period I am doing some Intermittent Fasting and eating lots of vegetables. I don’t know if this is causative of this increase, as in fact I was fasting already by about a day when I had the drawing. But there was already a problem BEFORE I started this regimen. I already saw one of the two fractions being twice the maximum limit. The only possibility that it’s Gilbert Syndrome, is that I have a variation of the syndrome since not everyone with GS has the same cause for it. Usually only one of the two fractions is above limits.
And if it wasn’t enough, my creatinin is constantly slightly below the limit:
Creatinin 0.77 mg/dl (0.8-1.3)
Any thoughts?
Find out if it’s Gilberts or if that is a direct result of liver damage. That’s what I’d do. There are enough liver damage stories around here as well to warrant that suspicion. OH and just a thought but it could possibly still like over-active autonomous system or whatever but this is pr much impossible to test on so don’t focus on that.
Also… I wouldn’t worry about creatine in your condition, unless you know EXACTLY what for and what amounts to take. Creatine has fucked up many people here in a similiar fashion much like Milk Thistle messed up lot of people. You can read about it from my member story (it should be interesting in that regard) + basically do a forum search on word “creatine”.
PS. If you know basic chemistry, you’d also know that the creatine monohydrate gym/bodybuilders use routinely is basically just creatine, it only has a 1 hydrate molecule connected to the actual molecule. It only affects the molecular weight than the effect/attributes of the molecule usually. Maybe you could get the last hydrate molecule out from it if you heated it long enough in high temp + store it in a anti-hydration containers (basically silica) or something.
PSS. For your autoimmune thyroid… if you want, i can email you pr exact guidelines to fix that (its a file). it would still be pretty important that you cut out ALL grains whatsoever as theres many anecdotes reporting (in STTM) that they’re autoimmune/thyroid malfunction problems disapeared as they started avoiding all grains, including pseudo grains (quinoa etc). Trust me, you don’t want to prolong your autoimmune attack on your thyroid for any longer, cos it gets pr much destroyed every day while your bodys at it.
Thank you very much for the help gefinauser. I have to wait until tuesday but I’ll look into this undoubtly.
About the over active autonomous nervous system, I have been diagnosed with that (precisely sympathetic nervous system hypertone), because of pretty high tachycardia. Don’t know if you were refeering directly to my condition or because you know that over active ANS can lead to high bilirubin.
About the creatinINE, I know it can be due to muscle atrophy, but also to kidney damage or hepatic insufficiency. My doubt was more on kidney damage, because low creatinine is a common marker of kidney damage. I surely lost muscles mass because of fin, but if that was the cause I would probably go at the gym without taking supplements (I stopped taking supplements, there’s too much uncertainity). Thank you for the hint on creatine, I read something about it messing with people here but not much.
The autoimmune thyroiditis apparently faded somewhat, I think it was triggered by acute stress I went on for some months because of PFS. Actually I was a heavy pasta eater . Anyhow, I’m on a 90% raw-vegetable diet now; will have to look better into this and take new readings for my thyroid. If the problem is still there I’ll have to look better into this as you suggest. But yes, if it’s not a problem that file could be useful thank you. Don’t know if you can send through PM. Maybe you can attach to this thread? otherwise I’ll send you my email.
Funny/Not funny, I also tested high in bilirubin [1.5, range: 0.2-1.3], the principal indicator of Gilbert’s syndrome. We are going to re-test (the initial result was seen in one of my first round of blood tests, but largely ignored due to the other issues) to confirm the result. Just a hunch, but my assumption would be that the liver is either damaged from the FIN or working overdrive to produce the missing hormone, rather than the opposite, that the Gilbert’s syndrome has affected our ability to process fin.
Has anyone else come back with high bilirubin T?