Found this interesting… lists various pathways affected by Finasteride, and genes.
Genetic interactions of Finasteride:
ctd.mdibl.org/detail.go?view=ixn … cc=D018120
GABRD = GABA-A Delta receptor
(Neuroactive ligand-receptor interaction)
Pathway affected: genome.jp/dbget-bin/show_pat … +ko:K05184
Genes affected: genome.jp/dbget-bin/get_link … NES+EGENES
SRD5A1 = 5alpha reductase type I
(Androgen and estrogen metabolism)
(Bile acid biosynthesis)
Cytochrome P450 substrates
Finasteride metabolized by CYP3A4
Bile acid synthesis Pathway affected: genome.jp/dbget-bin/show_pat … 0+1.3.99.5
5AR pathways affected:
genome.jp/dbget-bin/show_pat … 0+1.3.99.5
Enzymes & genes affected: genome.jp/dbget-bin/www_bget?enzyme+1.3.99.5