It’s a good question, it’s only an opinion based on this : some supplements need just one dose to have an effect, others need to build up in the system, the longest duration I have seen in a drug or supplement to have an effect is around two months so I like to give things I am unsure around this long so I can be confident I gave it a chance.
Basically I would assume it probably wouldn’t work in one dose, that it might work in 3 weeks and would definitely have worked in 2 months.