Is there a difference (or a substantive difference) in the mechanism of action? Natural 5ar inhibitors are probably less potent. Distinguishing between fin and natural 5ar inhibitors is relevant because certain natural 5ar inhibitors are potentially valuable for recovery. Sympathetic overactivity, a problem for some PFS sufferers, causes inflammation, which turmeric (allegedly a 5ar inhibitor) can address. Ditto amla (gooseberry) powder for inflammation, among other things. A synthetic 5ar inhibitor might have negaitive effects a natural one wouldn’t. And there’s likely a pretty big difference in potency. Any thoughts on this?
There’s not much difference. People get side effects micro-dosing fin so none of them are safe.
There are some people can tolerate different doses, but it depends on the body and luck.
I wouldn’t recommend either but I think saw palmetto is alot safer than fin.
I took saw palmetto for a year before I took fin without it causing me any obvious problems.
Fin is probably at least 10 times stronger than saw palmetto.
Can you expand on this a little, please?
They have properties, aside from possibly inhibiting 5AR (naturally as opposed to synthetically), that can make certain aspects of PFS better. You’d be hard pressed to find a better anti-inflammatory than turmeric, for instance. Even if it inhibited 5AR to a degree, you might get more T/DHT production on balance, because of the reduction in inflammation.
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Probably geared more towards people who are on the recovery path and no longer have fundamental androgen production/receptivity issues.
From the full text version of the study:
Men taking SPHB had a significant decrease in prostate tissue levels of DHT from baseline to 6 months of treatment (p = 0.005). However, this reduction was not statistically significant when compared to the placebo group. The 6-month decline in DHT for the SPHB group was 32%. In comparison, the finasteride effect on prostate tissue levels of DHT was an 80% reduction compared to untreated men