breastcancer.org/treatment/targeted_therapies/new_research/20090618c.jsp
After three days of exposure to trastuzumab in vitro, the previously ER-negative cells exhibited upregulation of ER±, Gauri Sabnis, PhD, of the University of Maryland in Baltimore, said at the Endocrine Society meeting.
just a theoretical idea. if we have problem with our Androgen receptor then can it be possible to develop any med which can turn our Androgen be unregulated just like ER-negative cells?