The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome , prevent noise-related hearing loss, fight certain types of prostate cancer , and even enhance cognition in healthy animals.
Sounds promising, although probably far away. Could be the biggest breakthrough in neurological treatment history. I hope this is true and ISRIB finds its way to the market within a few years. That said, it does sound a bit like those overenthusiastic science magazine stories. They would have to do a lot of testing to rule out serious side effects with such a mechanism, especially long term if necessary.
I’m personally convinced that PFS definitely falls within this category of cellular/molecular brain damage/dysregulation. I have definitely experienced cognitive problems and hopefully it can affect libido and sleeping issues as well.
It’s nice to see that a guy at Baylor is involved. Once this ISRIB thing takes flight maybe he and Dr. Mohit Khera are willing to try treatment on a PFS patient.