Dr. Jacobs' protocol

Those of us who have seen Dr. Jacobs know the 1st thing he tries is TRT. I know alot here have tried TRT and most have not had success. Wondering if anyone who has tried this protocol with Jacobs has had any success yet. If you dont feel comfortable posting in the forum please PM me.

I think its madness going straight on to TRT especially considering a lot of reports from people on TRT - very few report real improvements in libido etc, which is one of the main problems. Not to mention other problems that TRT brings.

For people on low testosterone the likes of HcG etc is surely a better option and even that shouldn’t be first base.

Very simplistic approach by Dr Jabcobs imo.

He must have something in mind when he prescribes this I have to guess. When I finish clomid/t3 I will probably go on TRT for 3 to 6 months in the absence of any other possible treatments. Would be fine if it didnt return my libido. If this provides enough androgens to my penis to help the atrophy and pain then I’m happy for now. iwontgiveup said TRT brought his relative size back. I guess it can also help with my fatigue and depression. Just would be nice if we had ONE example where Dr. J was treating someone successfully…anyone?

I have also asked Jacobs his opinion of oxytocin w/TRT. Hopefully he will get back to me on that.

I’m sure Dr. Jacobs is testing your neurotransmitters as well…right???

When your on finasteride, it’s increases your estrogen levels, blocks GABA, and also causes thyroid dysfunction. Thyroid dysfunction or Hypothyroidism can cause high Norepinephrine and cause a imbalance of other neurotransmitters(dopamine/serotonin). High Norepinephrine can cause chronic Erectile Dysfunction. Adrogenic beta blockers that block some Norepinephrine receptors such as Yohimbine were helpful to me in the past, while jacking my Testosterone over 1300 on clomid did nothing. I never understood why Yohimbine was so helpful now.

I’m sure Dr. Jacobs is looking at the whole picture, because it is very important, that Thyroid(High Normal T3, T4, and a T3/RT3 ratio above 20), Adrenals(DHEA, Cortisol etc etc…), Testosterone levels, and Neurotransmitters are at optimal levels. Neurotransmitters are a bit more tricky because there is more balancing that needs to be done. Optimize EVERYTHING first before going on TRT, see where your base Testosteorne levels are at when everything is optimized. If you are still feeling like crap, and everything else is optimized, then TRT could be of help.

I assume Dr. Jacobs wants to put you on oxytocin because that is something that is present in the prostate for spontaneous erections. Finasteride could of destroyed our natural production of oxytocin in the prostate, thus why we are having some issues down there as well.

Boston, I would recommend having Dr. Jacobs do a Plasma Catechlomine test(Norepinehphrine, Epinephrine, Dopamine) as well.

Good Luck

Anonn, your posts are always well thought out. Your right, one thing we do know is sky high Testoserone has never been the answer.

Neither Shippen or Jacobs have mentioned neurotrans tests. I will ask Dr. Shippen, since Im talking to him on Wednesday anyway, for those tests you recommended. Maybe I’ll go back on the yohombine and see how I feel.

I have emailed Dr. Jacobs office a few days ago for a script for oxytocin. He has not mentioned the drug in the past though. Is there a test for oxytocin? Oxytoncin increases 5AR activity yes?

Too bad there isn’t a counter finasteride drug to do exactly what fin does in reverse.