Dr. Alan Jacobs Patients: Please report your experience

What kinds of treatments did you undertake with him, if you don’t mind me asking?

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Yeah course. Ask away. I’ve probably been on about 20 different permutations of medicines and dosages. Basically try a regimen for a month, get blood tested, then reassess with him. I’ve tried all these: Ropinirole, cabergoline, bupropion, liothyronine, levothyroxene, methimazole, clomid, aromasin, testosterone gel and injections. Have cut back a lot of the medications and currently taking:

25 mg / once weekly of aromasin
1 ML t-injection of 100mg / weekly
150 mg / daily of bupropion

I’m trying to wean off bupropion. I can never seem to get my thyroid levels right. My T levels are always through the roof and above normal levels but doesn’t help libido, which is the only thing I care about at this point. Estrogen is in check. Pretty discouraging overall. Just started trying out veganism to see if that helps at all.

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Thanks for that enlightening rundown. Did any of the drugs make any difference to any of your symptoms? Did any make things better, or worse?

None made me worse. Depression and anxiety improved with the anti-depressants. The hormones have helped with memory fog which was bad for a while. I have outlier days where I’ll feel kind of normal in terms of libido, nothing like I was pre-PFS, but then I revert to feeling back to the new PFS me. Also tried a drug Addyi with Dr. Goldstein that had no effect. Have you had any success/improvements in your condition with anything?

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The only thing which was really worked for me has been probiotics of the Lactobacillus reuteri strain. There have been times where it has completely reverse PFS symptoms but other days where it is less effective. Long term use gives me an upset stomach so I only use it sporadically.