DHT induces expression of 5AR

pnas.org/content/88/18/8044.full.pdf

This paper suggests that the presence of DHT itself can induce the expression of 5AR.

It would be interesting to hear from people who have tried supplementing DHT directly about their experiences. For example, how long have you supplemented DHT, what dose did you use?

Apart from heavy weights and DHT, does anyone else know of any other documented ways to increase expression of 5AR?

Do a search on proviron or andractim

Forget Andractim, she’ll shut your HPTA

Take Proviron, is the best and not shut your HPTA (in normal doses)

You can use a GOOD Triblus together with Proviron

I think Mesterolone (Proviron) is a synthetic derivative of DHT, while Andractim is the biological equivalent of DHT, and therefore closer to what was being talked about in the study, as well as closer to what our bodies have evolved to make use of.

It seems that all of these hormones shut down the HPTA to some extent as the androgens are not being internally generated. So some kind of PCT after the DHT treatment would be appropriate I guess. The basic idea from the paper is that DHT could help our bodies to increase expression of 5AR back to the levels before fin inhibited them.

And another plus point is that DHT is not converted by aromatase to estrogen.

But as many problems seem to go beyond simple consequences of 5AR deficiency, this can only be just a starting point…

Supplementing AndroHard (DHT prohormone) was part of user CDNuts’ recovery protocol – along with PCT. But AndroHard is no longer available and he seems to think there isn’t anything on the market that really replicates its actions. He also maintains that AndroHard was probably a small part of his recovery – that fasting, paleo diet, exercise regimen, positive attitude/sleep/meditation were the real cornerstones. He also took some natural t-boosters. Others (like me) wonder if AndroHard wasn’t a bigger part of his recovery. I’m really interested in experimenting in this area.

RecentQuitter, got your PM thanks. Can’t respond direct yet as I am still too new here so can’t send PMs yet…

I think there could be something in this. I think the main problem with DHT supplementation is that, as with all of these steroids it can shut down the HPTA. So I am doing a lot of research this time before starting anything that might fuck me up any more than fin did.

One line of enquiry I am looking into at the moment can be found at the following link. I think someone linked to it here a long time ago too, but the thread wasn’t picked up on.

The idea is that naloxone can help to prevent HPTA shutdown while cycling hormones.
bluelight.org/vb/threads/685 … d-Naloxone

If this is true it could be a new approach to treating ourselves, but I need to look into it more. Would appreciate you and anyone else looking into this so we can evaluate its potential…

your and our answer is here guys. Dont search. This is my 5th year after quit when i was 19

Just run one or several cycles on masteron/proviron. And check your thyroid functions together with Androgens.
(But i am not sure if gene mutation occurs in expression level of 5ar enzyme in the long run.
But still you have chance if you use DHT.)

Check 5AR defeciency tretment also.
emedicine.medscape.com/article/9 … ment#a1127

Makes sense, but also worth noting a lot of people have felt worse while taking DHT supplements. One of the theories now is that certain DHT metabolites, have estrogenic components.

However I do think it makes sense to maintain high levels of DHT after a peroid of deprivation. The presence of androgens will regulate the activity of enzymes, so it’s important to keep them ticking over.

I’ve tried Proviron, AndroHard, Masteron and Winstrol. I intend to try Andractim in the next few weeks.

i remember i have just boost DHT with poviron and cold turkey after months with nightmares, sleep problems, very very bad days have passed, now after 5 years i have get my morning wood back everyday. its all normal range i think but i guess a little less androgen ciculating because of my body hair or not i dont know just curious

dannyfc, what was your experience with Winstrol? I have read accounts of it being used to lower high SHBG levels when taken at a dose of 25mg per week.

Is high SHBG an issue for you?

Nothing I’ve done has any discernible effect on my libido.

My SHBG was very high after coming off Propecia. 77 nmol/L (lab range is 20-60 nmol/L. Most young men should have less than 30 nmol/L)

I’m going to test it again next week so will tell you if Winstrol effectively lowered it. In certain studies if SHBG does not respond to Winstrol it has been used as a diagnosis of androgen resistance.

guys are you checking for adrenal fatigue? this is also important. most of us have its symtomps

as far as i understand, you have to exercise to help remember your body how it works before on its own fully functional, because its lost most of his enzymes and unbalanced steroid system