If there is any real interest in some of these possible relations, this should be looked at systematically.
We can obviously only do so much with this atm, especially when it comes to Crispr.
Also with whats currently on the market, probiotics should be treated like drugs. Know what your looking at and why.
As far as SCFAs there are 3 at a ratio of 60:20:20 there could be an imbalance here as well or reduction that could drive things like immunity and metabolism in different directions.
^Also this might be a stopgap if there was any type of resolution, because of the fact that these are bacterial metabolites. SCFAs might not always be beneficial depending on how they could drive health and disease. Some bacteria can manufacture one SCFA from another, acetate to butyrate is one example of this.
As far as bacteria itself you’d maybe be looking at reduced numbers vs increased. Meaning certain bacteria could become dominant that shouldn’t be or not kept in check.
Id also say you do not need to have altered bowel functions to realize possible shifts that could manifest themselves in numerous ways.
Plenty of bacteria can “pinch hit” for one another, take carb digestion for example.
This doesnt mean this might not manifest itself in other ways outside of gi function,
especially when it comes to mental symptoms.
You’ve literally just seen that possible result in a Finasteride study.