Your cortisol-production-line is:
LDL-cholesterol -> preg -> prog -> 17 hydroxyprog -> 11 deoxycort -> cortisol
…and is backed up at progesterone.
You can get prog flushing through to cortisol (which is half the battle when recovering from PFS) by boosting your resting metabolic rate.
Same goes for your testosterone production line, which is “backed up” at androstenedione. ie: You can get androstenedione flushing through to testosterone (which is the other half the battle when recovering from PFS) by boosting your resting metabolic rate.
I know everyone wants to whinge about PFS incessantly and say its incurable, but if you’re prepared to actually do something which is simply an extension of what we’re doing on this forum to boost testosterone simply in males without having to supplement with any testosterone, and which has indeed worked for a few PFS suffers, then here’s what you need to know to beat PFS:
When our cells experience a sustained level of high resting metabolic rate, they will not tolerate low hormone levels of the other critial hormones (includes negative hormone feedback loops causing PFS symptoms). When our cells experience a sustained level of high resting metabolic rate they will circumvent any negative hormone-feedback-loops which are causing low levels of any of the critical hormones, and the collective actions of all of our cells, while behaving in this way, results in the whole-body restoration of normal hormone metabolisms.
Some PFS sufferers have successfully recovered their normal hormone function, and they did this by boosting their resting metabolic rate for a sustained time period (whether accidentally or deliberately). It’s the sustained increase in resting metabolic rate which drove the elimination of their PFS symptoms. ie: the sustained increase in resting metabolic rate was not a downstream effect of their health improvement. Ie: first comes the increase in resting metabolic rate, then only after that is maintained for an extended period, comes the restoration of their normal hormone metabolism.
The way to cause our cells to experience sustained high resting metabolic rate, is to provide them with plenty of preg, prog, T3 and T4. Unfortunately there are very few of us with sufficient experience to add all these ingredients on day 1 and achieve success in a few weeks. Since most of us are newbies when it comes to the combination of these hormone supps, therefore we need a reliable process whereby we can start with just one supplement, and successively add in each of the remaining supplements, while being able to determine which supplement is in excess or deficit. This reliable process is discussed in detail in Hormone Modulation Therapy 101 (HMT101) - search for “Phase 1”, and read down the “Phase 3” (inclusive).
The process described in HMT101 is what I call the “3rd generation male treatment plan”.
The difference between the way that PFS sufferers implement the 3rd generation male treatment plan, and the way an aged male implements the 3rd generation male treatment plan, is that once PFS sufferers have restored their high hormone levels, then they back out the supplements and their body takes over.
The way this occurs is that their body starts taking over before they back out their supplements, and so they start to experience the symptoms of excesses of preg, or prog, or T3 or T4 at dosages of these which were previously (eg: last week) helpful, and so they reduce their dosage, and over a period of several weeks (no more than a few months) they are gradually forced to reduce their hormone supplement dosages to zero.
If a PFS sufferer is an aged male, then the male will need to continue with a small maintenence dose of either preg, or T4 or both.
A skeptical medical professional adviser would only implement the 3rd generation male treatment plan based on safety, ie: as a therapeutic trial, not because he understands the mode-of-operation. ie: the majority of males (including PFS sufferers) only need to implement top-up doses of preg, prog, T3 and T4, and these can be backed out relatively easily and relatively quickly if any adverse symptoms occur which are not able to be resolved simply by tweaking the dosage of preg, prog, T3 or T4, as discussed in Hormone Modulation Therapy 101
If your medical professional adviser is a skeptic, and he’s not prepared to work with you to implement the 3rd generation male treatment plan based on safety (without understanding the biological mechanism), then you’ll need to work with another medical professional adviser who is prepared to work with you this way rather than continuing to beat your head against the wall working with a chimp.
