Do you think that GnRh agonist can cause the same sides as pfs? I don’t think so. this question about the use of leuprorelin in profile page? looks like leuprorelin sides are not permanent.
Following cessation of exogenous GnRH agonist it takes 5 to 8 days before normal gonadotropin secretion is completely restored.[18]
There is a study discussed in this thread showing persistent ED despite return of normal range T levels after GnRH therapy. There is also a patient community of post-GnRH sufferers, many with far more debilitating symptoms than the typical PFS case.