Bunch of studies

I stumbled across this because I can’t get sleep and I want everyone to get better…I’m noticing alot of people on this board have low LH and FSH levels…Where clomid and novladex can stimulate LH production, it has a tough time getting FSH levels up. The reason why our semen is watery is because of LOW FSH levels. They have not rebounded and are at the low level of the normal range (i believe the normal range is 2-18) I’m around the 2 level. Before propecia i had huge loads of semen, probably above the 10 level atleast.

Here is some more information along with a link…

elitefitness.com/forum/pct-p … 92190.html

"HMG is typically used to treat infertility . Basically, long term use of hcg at doses of 1000 i.u. 3 or more times weekly causes suppresion or insensitivity of Luetinizing hormone (lh - leutenizing hormone - ) and to some degree Follicle stimulating hormone (FSH - follicle stimulating hormone - ).

Body builders who dont respond to the classic PCT - post cycle therapy - schemes of low dose hcg and Clomid for a few weeks will definitley have a hard time with recovery and may encounter depression, a lacking sexual drive, low testicular weight along with low semen/sperm volume.

HMG is Follicle stimulating hormone (FSH - follicle stimulating hormone - ) and luetinizing hormone (lh - leutenizing hormone - ). This simply stimulates your natural test production and keeps hcg working optimally. Your sex drive and sense of well being come back more rapidly then with other treatmentsr as well as your potential for staying or becoming fertile.

I’m thinking HMG, HCG, and novladex could be the key remedy here…along with proper vitamins(for our brain to function normally.

I’m not a doctor, just some more food for though.

Adios!

Research this…I’m on a roll today! lol

Selective glucocorticoid receptor agonist

A selective glucocorticoid receptor agonist (SEGRA) is a type of experimental drug which shares many of the desirable anti-inflammatory properties of classical glucocorticoid drugs but with fewer side effects such as skin atrophy. As of December 2008[update], SEGRAs are being investigated in cellular[1] and animal models[2] of inflammation but none as yet has entered clinical trials.

Link

en.wikipedia.org/wiki/Selective_ … or_agonist

This is worth reading…Link below

ohsu.edu/ohsuedu/academic/so … chacke.pdf

Dissociation of transactivation from transrepression
by a selective glucocorticoid receptor agonist leads
to separation of therapeutic effects from side effects

Glucocorticoids (GCs) are the most commonly used antiinflammatory
and immunosuppressive drugs. Their outstanding therapeutic
effects, however, are often accompanied by severe and sometimes
irreversible side effects. For this reason, one goal of research in the
GC field is the development of new drugs, which show a reduced
side-effect profile while maintaining the antiinflammatory and
immunosuppressive properties of classical GCs. GCs affect gene
expression by both transactivation and transrepression mechanisms.
The antiinflammatory effects are mediated to a major
extent via transrepression, while many side effects are due to
transactivation. Our aim has been to identify ligands of the GC
receptor (GR), which preferentially induce transrepression with
little or no transactivating activity. Here we describe a nonsteroidal
selective GR-agonist, ZK 216348, which shows a significant dissociation
between transrepression and transactivation both in vitro
and in vivo. In a murine model of skin inflammation, ZK 216348
showed antiinflammatory activity comparable to prednisolone for
both systemic and topical application. A markedly superior sideeffect
profile was found with regard to increases in blood glucose,
spleen involution, and, to a lesser extent, skin atrophy; however,
adrenocorticotropic hormone suppression was similar for both
compounds. Based on these findings, ZK 216348 should have a
lower risk, e.g., for induction of diabetes mellitus. The selective GR
agonists therefore represent a promising previously undescribed
class of drug candidates with an improved therapeutic index
compared to classical GCs. Moreover, they are useful tool compounds
for further investigating the mechanisms of GR-mediated
effects.
inflammation

Link:

sciencedirect.com/science?_o … a6e2e36596

Abstract
The brain isozyme of creatine kinase (CKB) is a major component of the estrogen-induced proteins in the rat uterus. Hormonal specificity of this response was studied in cotransfection assays using the rat CKB promoter linked to the bacterial chloramphenicol acetyltransferase gene. Response was specific for estrogen as 17β-estradiol in the presence of estrogen receptor dramatically stimulated the CKB promoter. This induction was completely blocked by the estrogen antagonist ICI 164,384. Nuclear receptors for progesterone, androgen, glucocorticoid and vitamin D did not significantly activate the CKB promoter in the presence of their respective ligands. Creatine kinase (CK) activity was analyzed in decidualized mouse uterus to assess estrogenic activity in vivo. Upon oil stimulation, uterine horns of day 4 pseudopregnant mice underwent a dramatic outgrowth in response to endogenous progesterone. This response was accompanied by a significant decrease in CK activity from a control value of 1.44±0.25 to 0.38±0.08 IU/mg protein (P < 0.001), indicating that the action of estrogen was suppressed. Treatment of females one day prior to oil-stimulation with progesterone receptor antagonists, RU486 (Mifepristone) or ZK299 (Onapristone), or with a monoclonal antibody to progesterone (DB3), abolished decidualization, and also restored the CK activity to the control value. These results suggest that CK can be used as a specific cellular marker to detect unopposed estrogen action in the mouse uterus associated with progesterone withdrawal or receptor blockade.

Link:

manufacturersuccess.com/incr … id-gland-2

Does anyone know any vitamins or natural apart from exercise to increase the efficiency of the thyroid gland? Category: Increase Efficiency — admin @ 7:16 am —
October 20, 2009
My cousin has a thyroid issue and was wondering if anyone knew any vitamins or natural herbs apart from exercise and prescribed medications tht would help?
b complex are there any specific brands…idk one a day or something that u know of"?

Interference with thyroid hormone is often an underlying cause of hypothyroidism, which, in turn, is responsible for more than 100 different symptoms. There are many undesirable effects which include weight gain and fatigue that cannot be controlled by diet or exercise.

Commonly observed symptoms of Hypothyroidism include
Fatigue

Weight Gain

Dry Skin

Constipation

Intolerance to Cold/Heat

Muscle Weakness

Indigestion

Memory Loss

Menstrual Disorders

Infertility

Sleep Disorders

Swelling of Hands, Feet, Eyelids

Loss of Hair

Heart Palpitation

Premenstrual Syndrome

Emotional Instability

Unopposed estrogen (estrogen dominance) can interfere with thyroid hormone activity and is often a primary underlying cause of thyroid dysfunction.

Because estrogen and thyroid hormone have opposing actions (probably at the thyroid hormone receptor level) unopposed Estrogen will prevent the thyroid hormone from “completing its mission,” resulting in “hypothyroid symptoms.” This excess estrogen is often responsible for the symptoms of Hypothyroidism, despite normal serum levels of Thyroid Stimulating Hormone (TSH).

Natural Progesterone, however, re-directs the activity of estrogen by increasing the sensitivity of estrogen receptors and, most importantly, inhibits many of unopposed estrogen’s undesirable side-effects, which includes interference with thyroid hormone activity.

Most women who are plagued by the symptoms of hypothyroidism have found that thyroid function has been normalized within a few weeks of using a properly formulated Natural Progesterone Cream, in conjunction with proven Dietary- Lifestyle modifications.

Because natural progesterone most often has a normalizing effect on a sluggish thyroid, the use of thyroid medication may over-stimulate the thyroid gland. Consult your health care professional if you are taking prescription thyroid medication.

In addition to a properly formulated Natural Progesterone Cream, many informed women have found that supplementing with ten kelp tablets per day has a nourishing effect on thyroid function.

« Will exercise increase the efficiency of oxygen transport to the brain?Where to buy ultralight trike kit? »Horaayy…there are 5 comment(s) for me so far :wink:
#1
Try a B complex. It naturally helps metabolism and aids the Thyroid.
References :

Stump wrote on October 20, 2009 - 12:58 pm #2
These foods have an adverse effect on the thyroid gland and should be moderated or avoided: Cabbage, Kale, Cauliflower, Spinach, Brussels Sprouts, Soy beans, Turnips and Beans.

Avoid fluoride as it can interfere with absorption of Iodine, a mineral essential to thyroid health. Check w/your local water supplier to see if water contains added fluoride.

Supplement with Vitamins A, C, D, E, PABA, Calcium, Iodine, Selenium and Zinc. Selenium is essential. Get them at the health food store and buy a good brand.

Some alternative herbs are Carrageenan, Iceland Moss, Parsley, Kelp, Sarsaparilla, Ginseng and Ginkgo. Cayenne pepper can help with cold extremities.
References :

Janet S wrote on October 20, 2009 - 1:37 pm #3
Interference with thyroid hormone is often an underlying cause of hypothyroidism, which, in turn, is responsible for more than 100 different symptoms. There are many undesirable effects which include weight gain and fatigue that cannot be controlled by diet or exercise.

Commonly observed symptoms of Hypothyroidism include
Fatigue

Weight Gain

Dry Skin

Constipation

Intolerance to Cold/Heat

Muscle Weakness

Indigestion

Memory Loss

Menstrual Disorders

Infertility

Sleep Disorders

Swelling of Hands, Feet, Eyelids

Loss of Hair

Heart Palpitation

Premenstrual Syndrome

Emotional Instability

Unopposed estrogen (estrogen dominance) can interfere with thyroid hormone activity and is often a primary underlying cause of thyroid dysfunction.

Because estrogen and thyroid hormone have opposing actions (probably at the thyroid hormone receptor level) unopposed Estrogen will prevent the thyroid hormone from “completing its mission,” resulting in “hypothyroid symptoms.” This excess estrogen is often responsible for the symptoms of Hypothyroidism, despite normal serum levels of Thyroid Stimulating Hormone (TSH).

Natural Progesterone, however, re-directs the activity of estrogen by increasing the sensitivity of estrogen receptors and, most importantly, inhibits many of unopposed estrogen’s undesirable side-effects, which includes interference with thyroid hormone activity.

Most women who are plagued by the symptoms of hypothyroidism have found that thyroid function has been normalized within a few weeks of using a properly formulated Natural Progesterone Cream, in conjunction with proven Dietary- Lifestyle modifications.

Because natural progesterone most often has a normalizing effect on a sluggish thyroid, the use of thyroid medication may over-stimulate the thyroid gland. Consult your health care professional if you are taking prescription thyroid medication.

In addition to a properly formulated Natural Progesterone Cream, many informed women have found that supplementing with ten kelp tablets per day has a nourishing effect on thyroid function.

10 kelp tablets…thats a few