Body weight and finasteride

Does 1mg of finasteride have greater effects on a man who is shorter and weights less i.e. 5’4", 120lb than on a man who weighs more i.e. 6’5", 280lb.? I was also thinking that supplements I take to potentially help with finasteride side effects, such as omega three fatty acids and garlic, say to take a certain amount each day, but it seems logical that if a small man and a large man took the same supplements, they would have less effect on the larger man, right?