I’ve been thinking more and more about autoimmune prostatitis, as I feel it strongly correlates with my symptoms, so I’m creating this topic so we can share theories and treatments with regards to this condition.
I have two posts from this forum bookmarked on this topic:
viewtopic.php?p=53662#p53662
viewtopic.php?p=55822#p55822
A small introduction about myself, I tried propecia for only a few days 5 years ago. I developed prostatitis a few days later, and I’ve had pain for pretty much every single day since then. I’ve pursued the antibiotic route with no success, and the pelvic pain/trigger point therapy with equal success.
The only thing that gives me relief are Testosterone injections, which strongly correlates with what has been written about EAP (experimental autoimmune prostatitis). As does keeping my Estradiol low, with aromatase inhibitors. I’m currently having a relapse of symptoms because I didn’t notice the arimidex I was taking had expired, so I began having symptoms of high E2, and then prostatic inflammation significantly increased.
I’ve tried many things now, but only a couple of them targetting the autoimmune pathway, so I’d like to try these in the near future:
- eviprostat (antihistamine and mast cell stabilizer, user 19 had success with it)
- short trial of dexa or prednisolone (autoimmune conditions should respond to this, albeit not a good long term strategy)
- PEA (palmitoylethanolamide, down-regulates hyperactive mast cells)
- mepartricin (there were a couple of studies that had success using this in chronic prostatitis, apparently it works by reducing plasma and intraprostatic estrogen concentration. Neat!)
- cabergoline (I remember reading somewhere that decreasing prolactin would have a beneficial effect, as would decreasing estrogen, in EAP)
VDRA have also shown promise in regards to autoimmune prostatitis, I read somewhere that there was study on elocalcitol, but it didn’t meet expectations.