Just curious, refer to ‘why do some people react to this drug so poorly…’ thread
Yup. From memory I was on Grapefruit juice a few times a day in small doses to slow down phase 1 liver detoxification. This was from a different doctor than the one that prescribed me the finasteride, but it makes sense that this could have somthing to do with it.
The problem is though, I havnt touched grapefruit juice for over a year now and my sexual sides really kicked in hard when I quit the finasteride.
you say sexual sides kicked in after u quit but did you have any during usage? also did you ween off the drug or quit cold turkey
The sides were there right from the start, but just no-where near what they were when i quit the drug. Quitting the drug was the equivilent of chopping off my dick…it was that bad.
I stopped cold turkey and the first two days my whole system crashed…similar to when you crash coming off cortisone.
wow thats really unfortunate dude, I hope u are getting better.
sciencedaily.com/releases/20 … 160050.htm
Grapefruit has been known for almost 20 years now to increase the serum level of a good amount of pharmaceuticals. Recently, they found it can inhibit the absorption of certain drugs. The link above talks in more detail about this but doesn’t list the drugs. I’ve seen Propecia on some web sites that list the drugs but not on others.
If you haven’t touched grapefruit juice in over a year and that’s where your sides were apparant, maybe there’s a connection?
I have never had grapefruit in my life, and did not drink wine while on Fin, and had strong side effects the same way. The effects of the drug are underestimated, it is Merck’s fault, not the pacients fault.
Grapefruit is known to interact with certain drugs. So is quercetin apparently, which is a flavonol found in citrus fruits, red grapes, broccoli, onion, etc. This article below talks about the interactions between quercetin and estradiol, an estrogen medication. Analogously, maybe there’s an interaction b/w quercetin and finasteride?
The quercetin simply blocks the effects of estrogen by binding to the receptors, which if your taking estradiol in the first place, you would not want to happen. I don’t think it would react directly with fin.
the link below expressly states that quercetin interacts with propecia.
Seeing as we’re all off of propecia now, it shouldn’t matter.
What if the quercetin didn’t allow the propecia to metabolize when we took it, and since we not gone three days without consuming products with quercetin in it, the propecia is still in our system?
Dude, almost 99% of people didn’t take Quercetin or anything like that while consuming Fin. Looking for other reasons for why Fin messed us up is pointless, its due to the DRUG ITSELF and its MECHANISMS OF ACTION – not soy, quercetin or any other supplement or natural food product.
You are trying to draw connections where there are none to be made.
Agreed.
Let’s just say that people WERE taking quercetin with fin and that quercetin didn’t allow fin to be metabolized. If that was the case, the fin would have been processed out of our systems as waste. Stuff just doesn’t hang around inside the body. It is either used, stored, or eliminated. In my case, I’ve taken care of the used and I’ve fasted down to being rather thin, so any of it that was potentially stored is gone.
I believe the on going effects are due to some type of physical change within my system due to the action of the drug. The drug is long gone from me, yet I still suffer sides. Whether or not these changes can “unchange” themselves is yet to be seen.
If quercetin blocks propecia from being metabolized, then the drug gets clogged up in the system, and quercetin is in a lot of things – citrus fruits, red grapes, broccoli, red onion, cranberry, tomatoes. I was just trying to cover all the bases.
Drugs are either metabolized, stored or eliminated. They can’t get “clogged up in the system.” The body doesn’t work like that.
isn’t clogged up same thing as stored?
I’m sorry, but this is nothing but pseudo-science and is simply your personal opinion.
You can believe whatever you want, but the fact is Finasteride usage is at the core of our issues.
If you hadn’t taken Fin, you’d be fine right now – Quercetin or no Quercetin.
If you have something that you may or may not need in the future, do you put it away in a closet or garage or do you put it in the middle of the hallway in your house?
See the difference? They are not the same thing, no.