Anxiety improvement

Dear friends,
It has now been 4 months since I developed PFS after taking finasteride for an enlarged prostate for only 2 months. Though initially my worst symptom was severe depression, after about 2 months the main issue became severe anxiety. Benzos like Xanax and Ativan are poor long term options, buspar made me severely depressed, and SSRIs are not a good idea in PFS. Here are 2 things that helped me.

  1. Silexan: One of the physicians from Europe in the “Resources” section of PFSfoundation.org suggested “Lasea” (which in the US is known as silexan). Silexan is lavender oil in the form of a capsule. I did do some research and when I googled “silexan clinical trials” or “lasea clinical trials” I was plesantly surprised to see that there have been good quality clinical trials where silexan went head to head vs lorazepam (Ativan) and placebo, and also another trial where it went head to head vs Paxil and placebo. In both studies, silexan was shown to be as effective against anxiety as Ativan and Paxil after 10 weeks but unlike both these medications with their well known side effects, silexan side effects were same as in the patients taking placebo. I was told that it takes a full 2 weeks before you notice the improvement in symptoms and sure enough it did take 2 weeks. I have been on silexan for 1 month and my anxiety is certainly better. I have been very happy with the results. My anxiety levels have decreased by 30-50% so it has become much more manageable. I have had no side effects other than the one side effect reported as occasional mild burping with a lavender scent which is not at all unpleasant.

  2. Cognitive Behavioral Therapy (CBT): This has been the biggest surprise. I had never had any psychological issues prior to PFS so I never new a lot about CBT. Counseling was offered for free by my employer for employees in a lot of stress and I decided to take advantage of this offer though I should say that I did not have high expectations. My job requires a lot of thinking and difficult decision making and anxiety and fogginess had made it very difficult for me to do my job well. I was afraid I would have to quit my job. I was desperate. I had 2 sessions with the counselor and the advice she gave me made my life at work immensely better. She asked me to have photos of family members and places I love around my desk, to have objects from places that I love that I can actually touch around my desk, have other things associated with good times that I could touch. Finally she asked me to chose a very happy and vivid recent memory and use it to escape in my mind any time anxiety hit. I did all the above not expecting much. I had a couple of rocks from my favorite beaches on my desk along with a few photos and other objects. The improvement in how I managed to control stress and do my job was amazing. Everything changed and I can work as I did before I was hit by PFS. It is not that anxiety has resolved. It is still there. However between CBT and silexan I am able to function well at work.

Silexan is sold in health food stores under the name CalmAid. It is an 80mg capsule. It the studies 80mg or 160mg were used daily. I started taking 80mg daily (one capsule) and then increased it to 80mg twice a day. I have had no side effects from either dose.

Of course I can not tell whether silexan will help others but the results of the studies (which can be found online at “Pubmed”) were pretty convincing to me and in fact I have been helped a lot. I hope that others dealing with this awful syndrome will find these 2 treatments (silexan and CBT) helpful.

All the best.

Giatriko.

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I should add that in Germany, silexan (lasea) has been approved by the German FDA for treatment of anxiety based on the results of the trials I described above. I believe it has been approved by the FDA of a few other European countries for treatment of anxiety, again based on the results of the studies I described which can be found in “PubMed”.

Thank you for sharing this. I will give it a try since i need something to get down my stress/anxiety level.

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Lavender oil is a DHT blocker just a heads up to anyone considering using it

You might be forced to wait it out. My anxiety was bad for a time after getting PFS but after a year now I don’t have any anxiety at all. It might just go way on its own, depression usually does go away for most PFS people so anxiety probably does too.

I am of now for over 1 year and my stress/anxiety even increased over the last 5 months… The last month now i seem to have light improvements, will wait another month until trying the lavender oil.

Hi,

Normaly i wait before giving an update on something i have tried. But here i have to do it now after a week of taking Lasea (Silexan) for my stress/anxiety problems.
I have realy a strong improvment of my stress level after only a week of taking 1 pill a day. If before my level would have been 100% is it now good under 50%, perhaps 30-40%. A lot of things better managable than before.

I will report back after a few weeks more of taking it.

Thx @Giatriko for sharing this.

I fund this about Lasea:

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Hi Zodiac,
I am so glad that silexan has been helpful. I just don’t know why it is not being prescribed by doctors for their patients with anxiety. It seems such a better option to the available anxiety medications. I am continuing to use it and the slow improvement is continuing, though there are occasionally bad days still. The anxiety is nothing like it was before though. All the best.

Giatriko

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