Antidepressants?

I’m sure this topic has been posted somewhere, but I can’t seem to ever get the search function to work. Has anyone, with any degree of success (in any area of suffering from PFS), had luck with antidepressants? I’ve tried long enough to defeat my depression, but I feel like I can’t do it on my own. If my sexual side effects are irreversible, so be it. I just wonder how much depression weighs me down mentally and contributes to my brain fog and loss of interest in life. At the same time, I am also concerned that they might exacerbate the situation. Anyone with experience care to weigh in? Thanks.