I had been thinking about this a lot lately too. I took an SSRI way before I had PFS and it helped me deal with anxiety, depression, and OCD. Lately, these things have been returning for me, so I was considering taking the same SSRI again.
I believe most people here would discourage you from taking any antidepressants, as we may have already screwed up our brain chemistries as it is. There is no telling what adding another medication to the mix would do to our body/brain chemistries.
I would say if it is possible to fight depression effectively for you without meds, then try that first. If you do decide to go with meds, do your research and of course see a psychiatrist. No self medicating.
Just for a warning, there is a whole forum of people that claim they have a similar disorder to PFS from just using SSRI medication.