As we all know, it tends to happen people get windows from antibiotics. This was often related to the gut, but I found out something else. For the people who believe in gene silencing being the cause of our problems, this might fit into that picture. ‘‘Drugs that interfere with methylation include valproic acid, cholestyramine, oral contraceptives, PPIs, and antibiotics.’’
‘‘Antibiotics suppress colon tumorigenesis through inhibition of aberrant DNA methylation’’
‘‘Antibiotics like amoxicillin, sulfamethoxazole, doxycycline and dozens more. Antibiotics kill your intestinal microflora (what you call your probiotics). Without the friendly gut flora, you cannot produce vitamin B12 (methylcobalamin). You also cannot activate riboflavin or folate so therefore, your methylation is blocked.’’
Could it be that because of these interfering effects with methylation, it creates a window? What u guys think?
I just found out antibiotics are also HDAC inhibitors. This can explain a lot and seems to be even the more logical reason for improvement on antibiotics. It gives this temporary ‘‘unsilencing’’ effect while taking them, makes a lot of sense. I for instance feel better when I take sodium butyrate, also a HDAC inhibitor. Maybe this combination of decreasing methylation antibiotics do because of the reasons I mentioned above, and also being an HDAC inhibitor, can create these windows. @Belikewater