Another Research Paper Questions the Validity of Finasteride

General Discussion Media & Awareness
#1

“Twenty-five percent of men currently taking Finasteride or Dutasteride, popularly known as Proscar and Avodart, for the treatment of benign prostate enlargement (BPH), appear not to benefit from taking these medications,” Medical Press reports today.

“Those prescribed Propecia or Avodart for male pattern hair loss (known as alopecia) are also at risk for adverse events elicited by these drugs.”

The story here:

medicalxpress.com/news/2015-08-a … ement.html

And the study, in Endocrine Reviews and Metabolic Disorders, titled “Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know?” here:

link.springer.com/article/10.100 … 015-9319-y

#2

Rufus, Rastas, Johnson, Brown,

Whatcha gonna do when the rent comes 'round?

Whatcha gonna do 'bout it, Kenny Frazier? Whatcha GONNA do?

Is ya gonna sit there like a little psychopathic prick?

Or is ya gonna be a man and clean up Merck’s mess?

What would your late daddy do?

I can’t say, but I suspect he’d be a man and help clean up his own mess.

#3

Overnight, three media outlets in India have picked up Dr. Traish’s study.

Please click on each link (very important) to show your support for these outlets. The more traffic they see coming in, the more likely they will be to cover PFS in the future:

The Times of India

timesofindia.indiatimes.com/life … 679420.cms

The Deccan Herald

deccanherald.com/content/497 … s-may.html

focusnews.com/lifestyle/hair-gro … fe/115509/

#4

Add another media outlet to the batch

Tech Times:

techtimes.com/articles/79486 … gement.htm

Whatcha gonna do, KCF?
Whatcha gonna do?
How you gonna battle Vioxx Part II?
The longer you sit with your head in the sand,
The worse it’s gonna look,
When the #*%! hits the fan.

#5

And now, two more media outlets picking up Dr. Traish’s study. Please click on each to show your support:

Dalhi Daily News

delhidailynews.com/news/Comm … 440577984/

Wishesh

andhrawishesh.com/srungaram/ … study.html

#6

And yet another Indian newspaper picks up the story:

The Siasat Daily:

siasat.com/news/common-hair- … fe-822288/

#7

Reminder: Please click on all of the links to coverage of Dr. Traish’s latest finasteride study, to show your support for media picking up the story. If you can, please share the links as well and have others click on them.

Thanks:

medicalxpress.com/news/2015-08-a … ement.html

deccanherald.com/content/497 … s-may.html

timesofindia.indiatimes.com/life … 679420.cms

focusnews.com/lifestyle/hair-gro … fe/115509/

techtimes.com/articles/79486 … gement.htm

delhidailynews.com/news/Comm … 440577984/

andhrawishesh.com/srungaram/ … study.html

siasat.com/news/common-hair- … fe-822288/

#8

And one more that just ran:

empr.com/news/side-effects-b … le/435026/

#9

And now an interview with Dr. Traish, in MedicalResearch.com:

medicalresearch.com/author-inter … cts/17056/

(Whatcha gonna do, KCF, whatcha gonna do?)

#10

Good article, thanks.

#11

Yes, good to see a medical professional say on the record what needs to be done next. That will be substantive progress…

In this study we have made four recommendations for future research:

We suggest that future research should focus on the scope and scale and the degree of persistence of sexual side effects. This area of investigation remains controversial and requires urgent, well thought out and well-designed studies to ascertain if these drugs do indeed cause enduring sexual side effects in vulnerable patients. More importantly, the underlying pathology and epigenetics of these potential changes need be investigated and delineated, in order to develop better management strategies.

We point out to recent investigations demonstrating various adverse effects on glucose metabolism, insulin resistance and potentially type 2 diabetes. These studies raise additional concerns and require further investigations. Epidemiological studies suggesting that these agents may impact bone metabolism is of concern and also need be studied clinically.

The effects of 5α-RIs therapy on the peripheral and CNS is not fully understood and merits critical evaluation through fundamental basic and clinical research. The data reported by Melcangi and his colleagues challenges the current dogma and necessitates expanding such studies to understand the impact of these agents on the CNS in order to appreciate the potential impact on depression, dementia, AD and other CNS related disorders.

Finally, although there is only rudimentary data on the potential effects of these drugs on the dolichol phosphate pathway, the impact these agents may have on biochemical signaling and protein glycosylation is of critical importance and needs be investigated.
#12

And another website picks up the story:

sciencedaily.com/releases/20 … 155819.htm

The more the merrier.

#13

Re: the interview with Dr Traish, it is great to read:

“The assertions that these drugs are well-tolerated and safe are at best inaccurate and are unsubstantiated.”

and that there is an absolute acknowledgement of the drug’s potentially adverse effects on a whole myriad of biological systems, and not just sexual, which has tended to be the primary focus:

“Physicians need to make a careful re-examination of the impact of the potential adverse effects of these agents not only on sexual function and psychological well-being, but also on other health concerns such as diabetes, bone metabolism, vascular disease, dementia and cerebrovascular disease.”

#14

Agreed. And thanks for recognizing Dr. Traish’s efforts.

Along those same lines, I’d just like to remind everyone again to click on all the links below to show our support for all the sites that are helping to promote his research.

It DOES make a difference because the more traffic any post generates, the most likely the editors are to cover the issue again in the future:

medicaldaily.com/common-drug … ile-350252

medicalxpress.com/news/2015-08-a … ement.html

timesofindia.indiatimes.com/life … 679420.cms

deccanherald.com/content/497 … s-may.html

focusnews.com/lifestyle/hair-gro … fe/115509/

techtimes.com/articles/79486 … gement.htm

delhidailynews.com/news/Comm … 440577984/

andhrawishesh.com/srungaram/ … study.html

siasat.com/news/common-hair- … fe-822288/

empr.com/news/side-effects-b … le/435026/

medicalresearch.com/author-inter … cts/17056/

sciencedaily.com/releases/20 … 155819.htm

pfsfoundation.org/news/sugge … -medicine/

#15

Another two publications cover Dr. Traish’s study, one in Italy and one in Spain:

Totalita: Magazine Online di Cultura e Politica
totalita.it/articolo.asp?art … 4&rubrica=

ABC.es
abc.es/sociedad/20150827/abc … 62112.html

And note that ABC “is a Spanish national daily newspaper published in Spain. It is the third largest general-interest newspaper in Spain, and the oldest newspaper still operating in Madrid. ABC is often referred to as a newspaper of record from Spain, along with El País and El Mundo.”

#16

And one more – Peru’s La Republica:

larepublica.pe/27-04-2011/tratam … on-erectil

Again, please click on the links to all these publications to show your support.