If our condition is indeed due or partially due to a silencing of the AR signal and its associated genes via negative autoregulation could this discovery have a role in the answer?
“Babraham Institute scientists are involved in researching the role of another DNA chemical modification in mammals called 5-hydroxymethyl-cytosine (5hmC), which is believed to be important for stem cell function, helping to define how the body develops. 5hmC may be a separate epigenetic mark or possibly be part of the process which removes methyl groups from DNA, allowing genes to be switched on again.”
sciencedaily.com/releases/2012/04/120426143854.htm
Sorry in advance if this has been previously covered material. Seems new epigenetic markers are being discovered and the process of silencing or activating genes may be getting even more complicated. This field is moving quickly.
Thoughts?