Interesting find here…I actually purchased a supplment called “blueprint”. It contains agamatine and ALA.
Anyways here is some information on it. I just started taking it yesterday…will continue to take it for 1 month.
Currently I’ve been on Sustain Alpha for, toco 8, and endoamp 1 month along with some daily vitamins, and horny goat weed tea.
Going to give Blueprint and Diesel Test Hardcore a shot for 1 month, then revert back to sustain alpha for another 1 month and see how I feel.
Other than that I’ve been working out hardcore, trying to get in good shape. Going to put myself on a detox diet in 2 months…Basically gonig to drink green tea and eat vegetables(no meat) for 2-4 weeks.
More info on Agmatine down below:
Agmatine, an amine and organic cation, is an endogenous ligand at alpha 2-adrenergic and imidazoline (I-) receptors, to which it binds with high affinity. In addition, agmatine has properties of an endogenous neurotransmitter. Thus, agmatine (a) is locally synthesized in brain by a specific enzyme, arginine decarboxylase; (b) is stored in a large number of neurons with selective distribution in the CNS; © is associated with small vesicles in axon terminals that, at least in hippocampus, make synaptic asymmetric (excitatory) synapses on pyramidal cells; (d) is released from synaptosomes in a Ca(2+)-dependent manner; (e) can be enzymatically degraded by agmatinase in synaptosomes; (f) can be inactivated by selective reuptake; (g) blocks the ligand-gated NMDA receptor channel at sites distinct from ligand-binding and polyamine sites; and (h) has systemic actions when administered intraventricularly. Additionally, (i) agmatine is a precursor of brain putrescine and, hence, of higher polyamines, and (j) it competitively inhibits the activity of all isozymes of nitric oxide synthase. Agmatine meets most criteria to establish it as a novel neurotransmitter/neuromodulator in the CNS. However, agmatine differs from forms of clonidine displacing system with respect to distribution, bioactivity, and capacity to interact with antibodies raised to imidazoline-like drugs. Thus, there are multiple endogenous ligands of the imidazoline receptors, one of which is agmatine.