Advice please

What’s to say? you have already covered it

You could try and boost your testosterone using a number of methods; clomid, arimidex, t gel etc but so many of us have already done that and not felt benefits. You could try nettle root to lower SHGB.

What about thyroid and cortisol? are you planning on checking those?

Slightly low T4; low cortisol.

Whay would my T drop 200 points?? Any advice?

OK - so I went back to the urologist who had me wean off everything for several months. Balls are tiny and painful - ejaculation is a killer. He seemed to at least not dismiss the small balls.

Plan is another round of bloodwork and then clomid - start with a low dose and see. I mentioned Arimidex and he said we will see depending upon how far estrogen rises. I mentioned HCG and he said its VERY expensive and he did not necessarily endorse.

Right now I am in a bit of panic around nut size. Estrogen is high and I am putting on quite the spare tire. Pledged for New Years to start jogging and try to get rid of the gut. This should help circulation and also lower estrogen. Thinking about adding T4 fto the clmid protocol - I am always bordeline low for T4 and this should ramp things up a bit. Also considering the Max Milk Thistle given I think some of my issue is related to liver not getting rid of estrogen SHBG. Been drinking too much beer lately - kind of depressed.

Any thoughts?

Drop that since it raises estrogen and is probably contributing to the gut and depression. Eat more healthy, exercise and take Omega 3 fish oils to help counter the depression.

Other than that, try your Uro’s advice.

THX Mew - actually - I am taking vitamins/fish oil. I am hopeful this time I can exercise without bradicardia (extreme low heartbeat) which stopped me in my tracks right after giving up propecia.

I am open to the Clomid as I need to get my T back up but I will be watching the E closely . Even now it is still too high but nothing like before when it was out of range for males. Wish there was something to help my painful tiny balls…

Yes, I mentioned HCG to him and he would not bite

Did you ever have the ultrasound done?

What did it show?

OK - here are my labs related to T and Estrogen.
Ranges
Testosterone 250-1100
Free Test 35-155
Estradiol <39 for males
SHBG 9-45

Date 9/2010 Testosterone: 718 Free Test: 100.5 Estradiol: 55 (way high)
Date 1/2011 Testosterone: 711 Free Test: 87.5 Estradiol: 38 (high) SHBG: 66 (way high)
Date 10/2011 Testosterone: 512 Free Test: 54.8 Estradiol: 30 (high) SHBG: 54 (way high)
Date 1/2012 Testosterone: 721 Free Test: 106 Estradiol: 42 (way high) SHBG: 60 (way high)

A couple of notes - the 512 day was in one of my really bad days. Last test was a more “normal” day. Actually glad to see the Test bounce back to my normal range vs. the 200 point drop (lovely PFS swings). My doc was moving to Clomid if the test did not bounce back - not sure he will now. Anyway - for me it is clear the issue is both Estrogen levels and also SHBG. So I have tiny painful nuts but for now they are still working for testosterone production (maybe overtime) but the estrogen and Sex hormone binding globule is killing that.

BTW - since the 55 I have been very regular using dim - working to an extent but not enough…And WTF on the SHBG! Any comments/advice here?

Anyone? Does anyone have SHBG in this range?

Anyone have any input - doc visit is on Monday - Should I still try clomid? Try arimidex, etc.

Echoing Mew’s reply, give up beer, all alcohol in general for that matter. How’s your diet now?

Up to the holiday 12/25, diet was a bit poor. Since that time, very clean diet/limited alchohol - jogging exercise routine.

Still sky high estrogen and SHBG…

OK - here are my labs related to T and Estrogen.
Ranges
Testosterone 250-1100
Free Test 35-155
Estradiol <39 for males
SHBG 9-45

Date 9/2010 Testosterone: 718 Free Test: 100.5 Estradiol: 55 (way high)
Date 1/2011 Testosterone: 711 Free Test: 87.5 Estradiol: 38 (high) SHBG: 66 (way high)
Date 10/2011 Testosterone: 512 Free Test: 54.8 Estradiol: 30 (high) SHBG: 54 (way high)
Date 1/2012 Testosterone: 721 Free Test: 106 Estradiol: 42 (way high) SHBG: 60 (way high)

A couple of notes - the 512 day was in one of my really bad days. Last test was a more “normal” day. Actually glad to see the Test bounce back to my normal range vs. the 200 point drop (lovely PFS swings). My doc was moving to Clomid if the test did not bounce back - not sure he will now. Anyway - for me it is clear the issue is both Estrogen levels and also SHBG. So I have tiny painful nuts but for now they are still working for testosterone production (maybe overtime) but the estrogen and Sex hormone binding globule is killing that.

BTW - since the 55 I have been very regular using dim - working to an extent but not enough…And WTF on the SHBG! Any comments/advice here?

Wow - hate to say this but this site seems to be useless for advice/information sharing anymore. Not sure if folks have just stopped bothering but seems like there are just a few daily posters and everyone else has gone away. And the few daily posters are just interested in a few threads - evrything else just seems to die. Hopefully the folks who are no longer around are cured…

There not… I did mass messaging and got a considerable amount of replies back. Most people are feeling as bad as ever.

A lot of potential treatments have been weeded out as ineffective (i.e. testosterone replacement). This narrows the suggestion range. A lot of guys too have gone through the treatment routes and not found anything effective so there is less excitement behind the routes you’re inquiring about, not to mention that SHBG is one of the more difficult measures to bring down.

Given your estrogen is consistently high an estrogen blocker is a good avenue with which to start. Also read Xhorndog’s recent posts on diet if you haven’t yet.

This site is invaluable for sharing information. Unfortunatley, members want to talk about how we have candida or how stupid it is to think we have candida.

This site is so precious to us, it’s sad to see it not used to its full potential. When I first signed up here, my knowledge about our condition grew exponentially. But as my individual knowledge caught up with the collective knowledge, I came to a stand still. I grew frustrated, along with others. Bickering started over which theory was the stupidest.

I hope this vicious circle is coming to an end. And I believe it is. A few of us are rallying behind autoimmune theories and we are attempting to acquire the data needed to expand theories and come up with possible treatments. Imagine in a few months time when more and more members get immunoglobulin bloodwork done, and when awor presents his findings. Our knowledge will have grown exponentially.

Each member here has the possibilty to contribute the finding a cure to PFS. It could be something as small as getting bloodwork done and sharing your results. It could be just by donating money to awor’s team.

On the other hand, each member here has the possibility to set us back in finding a cure. And we’ve seen that before. Solon probably set us back a couple years with his nonsense and insanity. And as a result, xhorndog tapped out. We could’ve used his smarts, ambition and (seemlingly abundant) resources.

Listen - I 100% agree with the point about the bickering. I cannot even imagine the thought process of trashing others who are going though the same thing as myself. This whole portion of my life I would love to forget but I cannot.

I am really frustrated when I post and try to get ANY feedback and the few regular posters all want to talk about a very few threads. It makes me feel there are very few in the same situation as myself - which two years ago I did not.

Hey - and by the way - Go GIANTS!

Yeah baby - Giants in the Super Bowl!

So I went this a.m. to my urologist who was moving on to Clomid if the T did not push back up. He acknowledged that I have an estrogen problem (hooray) - I asked again about Arimidex. He saidhe did not know if it was still around (thought there was a recall). I assured him that many on the boards take it. So he asked which I would rather have - the Arimdex or the Clomid. I asked about both and he stated he would far prefer to try one at a time. He did not rule out using both down the line. So I have a script for Arimidex. I asked if maybe this was also something structural - I do feel it may be this in combination with fin getting my hormones fucked up. He did not really bite on that. He suggested it also might be the adrenals although in his words you don’t really look like someone suffering from that. He also said I really don’t look like someone with high estrogen - typically these guys are “fat” or pear shaped. I did tell him I have put on a gut which is strange as I have not totally over-eaten.

So I feel good about this - I have been asking various docs for arimidex for 1.5 years.

Now onto the dosage - he presribed 1 mg twice daily; pill form. I was not sure if this is typical dosage. I am following up with bloods in exactly one month.

What do you guys think. Thanks for any replies…

2mg per day sounds high. I think I recall on Crisler’s forum the suggested starting dose was 0.25mg and every 3 days at that. Do some research.